Transcription Factor

Accessions: 5nm9_A (3D-footprint 20231221)
Names: B3S7S5_TRIAD, MAD homolog, Mothers against decapentaplegic homolog, Mothers against DPP homolog, SMAD family member
Organisms: Trichoplax adhaerens, Trichoplax reptans
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: B3S7S5
Length: 122
Pfam Domains: 23-122 MH1 domain
Sequence:
(in bold interface residues)
1 ATLGIVHTLMCHRQGGESENFAKRAVESLVKKLKDKRDELDALITAVTSNGIQQSKCVTI 60
61 ARTLDGRLQVAGKKGFPHVIYSRIWRWPDLHKNELKHIKLCKFAFDLKLDHVCVNPYHYE 120
121 RV
Interface Residues: 44, 65, 67, 69, 74
3D-footprint Homologues: 4efj_A, 6fzs_A, 5od6_A, 6h3r_A, 5nm9_A, 5mey_A
Binding Motifs: 5nm9_A sCGcCC
Binding Sites: 5nm9_C / 5nm9_D
Publications: Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun 8:2070 (2017). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.