Transcription Factor
| Accessions: | 5flv_I (3D-footprint 20231221) |
| Names: | HOMEOBOX PROTEIN NKX-2.5, T-BOX TRANSCRIPTION FACTOR TBX5, T-box protein 5, TBX5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 226 |
| Pfam Domains: | 1-55 Homeobox domain 58-226 T-box |
| Sequence: (in bold interface residues) | 1 PRVLFSQAQVYELERRFKQQRYLSAPERDQLASVLKLTSTQVKIWFQNRRYKSKRQRVFL 60 61 HERELWLKFHEVGTEMIITKAGRRMFPSYKVVTGLNPKTKYILLMDIVPADDHRYKFADN 120 121 KWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKY 180 181 QPRLHIVKADSTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFR |
| Interface Residues: | 2, 40, 41, 43, 44, 47, 48, 51, 52, 55, 83, 204, 205, 221, 224, 225 |
| 3D-footprint Homologues: | 4cyc_A, 2h1k_B, 5flv_I, 3lnq_A, 2lkx_A, 1jgg_B, 1au7_A, 3a01_E, 2hdd_A, 1nk2_P, 6m3d_C, 1fjl_B, 5hod_A, 3rkq_B, 2r5y_A, 6a8r_A, 1b72_A, 3cmy_A, 2hos_A, 7psx_B, 5jlw_D, 6es3_K, 4xrs_G, 2ld5_A, 1puf_A, 7q3o_C, 1ig7_A, 5zfz_A, 2xsd_C, 1e3o_C, 7xrc_C, 4j19_B, 1le8_A, 1mnm_C, 1puf_B, 5zjt_E, 8g87_X, 1k61_B, 4qtr_D, 1o4x_A, 1zq3_P, 1du0_A, 3l1p_A, 6f59_B, 1xbr_B, 1h6f_B, 4a04_B, 2x6v_A |
| Binding Motifs: | 5flv_I CACnnTTGAAGnGg |
| Binding Sites: | 5flv_J 5flv_K |
| Publications: | Luna-Zurita L, Stirnimann CU, Glatt S, Kaynak BL, Thomas S, Baudin F, Samee MA, He D, Small EM, Mileikovsky M, Nagy A, Holloway AK, Pollard KS, Müller CW, Bruneau BG. Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis. Cell 164:999-1014 (2016). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.