Transcription Factor

Accessions: 1dgc_A (3D-footprint 20231221)
Names: Amino acid biosynthesis regulatory protein, GCN4_YEAST, General control protein GCN4
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P03069
Length: 55
Pfam Domains: 3-52 bZIP transcription factor
4-50 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 PAALKRARNTEAARRSRARKLQRMKQLEDKVEELLSKNYHLENEVARLKKLVGER
Interface Residues: 5, 6, 8, 9, 10, 11, 12, 13, 16, 17
3D-footprint Homologues: 7x5e_F, 1nwq_C, 6mg1_B, 1llm_D, 5t01_B, 5vpe_D, 2dgc_A
Binding Motifs: 1dgc_A CGTca
Binding Sites: 1dgc_B
Publications: König P, Richmond T.J. The X-ray structure of the GCN4-bZIP bound to ATF/CREB site DNA shows the complex depends on DNA flexibility. Journal of molecular biology 233:139-54 (1993). [Pubmed]
Related annotations: PaperBLAST

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