Transcription Factor
Accessions: | ZN384_HUMAN (HOCOMOCO 10), Q8TF68 (JASPAR 2024) |
Names: | CAG repeat protein 1, CAS-interacting zinc finger protein, Nuclear matrix protein 4, Nuclear matrix transcription factor 4, Trinucleotide repeat-containing gene 1 protein, Zinc finger protein 384, ZN384_HUMAN |
Organisms: | Homo sapiens |
Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q8TF68 |
Length: | 577 |
Pfam Domains: | 244-267 Zinc-finger double domain 255-271 C2H2-type zinc finger 256-278 C2H2-type zinc finger 256-278 Zinc finger, C2H2 type 271-294 Zinc-finger double domain 284-304 C2H2-type zinc finger 284-303 C2H2-type zinc finger 284-306 Zinc finger, C2H2 type 304-328 Zinc-finger double domain 316-331 C2H2-type zinc finger 317-339 C2H2-type zinc finger 317-339 Zinc finger, C2H2 type 332-355 Zinc-finger double domain 345-365 C2H2-type zinc finger 345-364 C2H2-type zinc finger 345-367 Zinc finger, C2H2 type 359-386 Zinc-finger double domain 373-397 Zinc finger, C2H2 type 373-398 C2H2-type zinc finger 380-398 C2H2-type zinc finger 389-413 Zinc-finger double domain 403-425 Zinc finger, C2H2 type 417-444 Zinc-finger double domain 432-456 C2H2-type zinc finger 433-455 Zinc finger, C2H2 type 433-456 C2H2-type zinc finger |
Sequence: (in bold interface residues) | 1 MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGLAPPHYPTLLTVPASVS 60 61 LPSGISMDTESKSDQLTPHSQASVTQNITVVPVPSTGLMTAGVSCSQRWRREGSQSRGPG 120 121 LVITSPSGSLVTTASSAQTFPISAPMIVSALPPGSQALQVVPDLSKKVASTLTEEGGGGG 180 181 GGGGSVAPKPPRGRKKKRMLESGLPEMNDPYVLSPEDDDDHQKDGKTYRCRMCSLTFYSK 240 241 SEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHIRIHSGAKPYSCNFCEKSFRQLSHLQ 300 301 QHTRIHSKMHTETIKPHKCPHCSKTFANTSYLAQHLRIHSGAKPYNCSYCQKAFRQLSHL 360 361 QQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQSHRRQHNKDKPFKCHNCHRAYTDAASLEV 420 421 HLSTHTVKHAKVYTCTICSRAYTSETYLMKHMRKHNPPDLQQQVQAAAAAAAVAQAQAQA 480 481 QAQAQAQAQAQAQAQASQASQQQQQQQQQQQQQQQQPPPHFQSPGAAPQGGGGGDSNPNP 540 541 PPQCSFDLTPYKTAEHHKDICLTVTTSTIQVEHLASS |
Interface Residues: | 239, 241, 242, 245, 266, 267, 268, 269, 270, 273, 274, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 307, 317, 327, 328, 329, 330, 331, 333, 334, 337, 338, 355, 356, 357, 358, 359, 361, 362, 366, 385, 386, 387, 388, 389, 390, 391, 392, 413, 414, 415, 416, 417, 419, 420, 424, 443, 444, 445, 446, 447, 449, 450, 453, 487, 500, 502, 504, 505, 508, 512 |
3D-footprint Homologues: | 8ssq_A, 5und_A, 8ssu_A, 5yel_A, 3uk3_C, 5v3j_F, 4x9j_A, 2i13_A, 8gn3_A, 1llm_D, 1f2i_J, 5k5i_A, 7w1m_H, 1tf6_A, 4m9v_C, 6e94_A, 6a57_A, 7txc_E, 5yj3_D, 6ml4_A, 7ysf_A, 2jpa_A, 1ubd_C, 7n5w_A, 6jnm_A, 5kkq_D, 5ei9_F, 1mey_C, 5kl3_A, 6wmi_A, 2kmk_A, 5k5l_F, 8h9h_G, 7eyi_G, 7y3m_I, 2lt7_A, 1tf3_A, 6blw_A, 8cuc_F, 7y3l_A, 2wbs_A, 6u9q_A, 2gli_A, 1g2f_F, 2drp_D |
Binding Motifs: | ZN384_HUMAN.H10MO.C|M01629 gsAAAAAvycks MA1125.1 wwwmAAAAAAaa MA1125.2 AAAAAAaa |
Binding Sites: | MA1125.2.17 / MA1125.2.20 MA1125.2.7 MA1125.2.15 MA1125.2.1 / MA1125.2.10 / MA1125.2.11 / MA1125.2.12 / MA1125.2.14 / MA1125.2.16 / MA1125.2.19 / MA1125.2.2 / MA1125.2.3 / MA1125.2.4 MA1125.1.1 MA1125.1.10 MA1125.1.11 MA1125.1.12 MA1125.1.13 MA1125.1.14 MA1125.1.15 MA1125.1.16 MA1125.1.17 MA1125.1.18 MA1125.1.19 MA1125.1.2 MA1125.1.20 MA1125.1.3 MA1125.1.4 MA1125.1.5 MA1125.1.6 MA1125.1.7 MA1125.1.8 MA1125.1.9 MA1125.2.13 MA1125.2.18 MA1125.2.5 / MA1125.2.8 / MA1125.2.9 MA1125.2.6 |
Publications: | Thunyakitpisal P., Alvarez M., Tokunaga K., Onyia J. E., Hock J., Ohashi N., Feister H., Rhodes S. J., Bidwell J. P. Cloning and functional analysis of a family of nuclear matrix transcription factors (NP/NMP4) that regulate type I collagen expression in osteoblasts.. J. Bone Miner. Res. 16:10-23 (2001). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.