Transcription Factor

						

			
Accessions: Q08AN1 (JASPAR 2024)

			
Names: ZN616_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q08AN1
Length: 781
Pfam Domains:      7-47 KRAB box
  184-205 C2H2-type zinc finger
  185-207 C2H2-type zinc finger
  185-207 Zinc finger, C2H2 type
  200-223 Zinc-finger double domain
  212-232 C2H2-type zinc finger
  213-235 Zinc finger, C2H2 type
  213-235 C2H2-type zinc finger
  228-250 Zinc-finger double domain
  241-263 C2H2-type zinc finger
  241-263 Zinc finger, C2H2 type
  241-263 C2H2-type zinc finger
  256-279 Zinc-finger double domain
  269-280 C2H2-type zinc finger
  269-291 Zinc finger, C2H2 type
  269-291 C2H2-type zinc finger
  283-307 Zinc-finger double domain
  296-307 C2H2-type zinc finger
  297-319 Zinc finger, C2H2 type
  297-319 C2H2-type zinc finger
  311-336 Zinc-finger double domain
  325-343 C2H2-type zinc finger
  325-347 Zinc finger, C2H2 type
  325-345 C2H2-type zinc finger
  339-364 Zinc-finger double domain
  352-373 C2H2-type zinc finger
  353-375 Zinc finger, C2H2 type
  353-375 C2H2-type zinc finger
  367-391 Zinc-finger double domain
  381-403 C2H2-type zinc finger
  381-401 C2H2-type zinc finger
  381-403 Zinc finger, C2H2 type
  396-419 Zinc-finger double domain
  410-431 C2H2-type zinc finger
  410-429 C2H2-type zinc finger
  410-431 Zinc finger, C2H2 type
  424-447 Zinc-finger double domain
  436-448 C2H2-type zinc finger
  437-459 Zinc finger, C2H2 type
  437-459 C2H2-type zinc finger
  452-475 Zinc-finger double domain
  465-475 C2H2-type zinc finger
  465-487 Zinc finger, C2H2 type
  465-487 C2H2-type zinc finger
  480-503 Zinc-finger double domain
  492-506 C2H2-type zinc finger
  493-515 Zinc finger, C2H2 type
  493-515 C2H2-type zinc finger
  508-531 Zinc-finger double domain
  520-541 C2H2-type zinc finger
  521-543 Zinc finger, C2H2 type
  521-543 C2H2-type zinc finger
  536-559 Zinc-finger double domain
  548-569 C2H2-type zinc finger
  549-571 Zinc finger, C2H2 type
  549-571 C2H2-type zinc finger
  564-587 Zinc-finger double domain
  576-599 C2H2-type zinc finger
  577-599 Zinc finger, C2H2 type
  577-599 C2H2-type zinc finger
  592-615 Zinc-finger double domain
  604-625 C2H2-type zinc finger
  605-627 C2H2-type zinc finger
  605-627 Zinc finger, C2H2 type
  620-643 Zinc-finger double domain
  632-643 C2H2-type zinc finger
  633-655 C2H2-type zinc finger
  633-655 Zinc finger, C2H2 type
  647-672 Zinc-finger double domain
  660-680 C2H2-type zinc finger
  661-683 Zinc finger, C2H2 type
  661-683 C2H2-type zinc finger
  675-700 Zinc-finger double domain
  688-709 C2H2-type zinc finger
  689-711 Zinc finger, C2H2 type
  689-711 C2H2-type zinc finger
  703-727 Zinc-finger double domain
  717-739 Zinc finger, C2H2 type
  717-739 C2H2-type zinc finger
  731-754 Zinc-finger double domain
  744-767 C2H2-type zinc finger
  745-767 Zinc finger, C2H2 type
  745-767 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MATQGHLTFKDVAIEFSQEEWKCLEPVQKALYKDVMLENYRNLVFLGISPKCVIKELPPT   60
  61 ENSNTGERFQTVALERHQSYDIENLYFREIQKHLHDLEFQWKDGETNDKEVPVPHENNLT  120
 121 GKRDQHSQGDVENNHIENQLTSNFESRLAELQKVQTEGRLYECNETEKTGNNGCLVSPHI  180
 181 REKTYVCNECGKAFKASSSLINHQRIHTTEKPYKCNECGKAFHRASLLTVHKVVHTRGKS  240
 241 YQCDVCGKIFRKNSYFVRHQRSHTGQKPYICNECGKSFSKSSHLAVHQRIHTGEKPYKCN  300
 301 LCGKSFSQRVHLRLHQTVHTGERPFKCNECGKTFKRSSNLTVHQVIHAGKKPYKCDVCGK  360
 361 AFRHRSNLVCHRRIHSGEKQYKCNECGKVFSKRSSLAVHRRIHTVEKPCKCNECGKVFSK  420
 421 RSSLAVHQRIHTGQKTYKCNKCGKVYSKHSHLAVHWRIHTGEKAYKCNECGKVFSIHSRL  480
 481 AAHQRIHTGEKPYKCNECGKVFSQHSRLAVHRRIHTGEKPYKCKECGKVFSDRSAFARHR  540
 541 RIHTGEKPYKCKECGKVFSQCSRLTVHRRIHSGEKPYKCNECGKVYSQYSHLVGHRRVHT  600
 601 GEKPYKCHECGKAFNQGSTLNRHQRIHTGEKPYKCNQCGNSFSQRVHLRLHQTVHTGDRP  660
 661 YKCNECGKTFKRSSNLTAHQIIHAGKKPYKCDECGKVFRHSSHLVSHQRIHTGEKRYKCI  720
 721 ECGKAFGRLFSLSKHQRIHSGKKPYKCNECGKSFICRSGLTKHRIRHTGESLTTKLNVTR  780
 781 P
Interface Residues: 177, 198, 199, 201, 202, 224, 226, 227, 230, 252, 253, 254, 255, 258, 279, 280, 282, 283, 286, 308, 309, 310, 311, 313, 314, 325, 335, 336, 337, 338, 339, 342, 363, 364, 366, 367, 370, 392, 393, 394, 395, 398, 448, 450, 451, 454, 475, 476, 477, 478, 479, 480, 482, 486, 503, 504, 506, 507, 510, 532, 533, 534, 535, 536, 537, 538, 542, 559, 560, 561, 562, 563, 565, 566, 587, 588, 589, 590, 591, 593, 594, 595, 596, 597, 600, 615, 616, 617, 618, 619, 620, 622, 623, 644, 645, 646, 647, 649, 650, 654, 672, 673, 674, 675, 678, 684, 698, 700, 702, 703, 706, 710, 727, 728, 729, 730, 731, 734, 755, 756, 758
3D-footprint Homologues: 4pog_H, 2lt7_A, 7ysf_A, 1ubd_C, 8cuc_F, 7y3l_A, 3uk3_C, 1tf3_A, 4x9j_A, 1llm_D, 5kl3_A, 1f2i_J, 2wbs_A, 5yj3_D, 2kmk_A, 5yel_A, 5k5l_F, 7n5w_A, 6jnm_A, 8ssu_A, 6ml4_A, 2gli_A, 7w1m_H, 8h9h_G, 5ei9_F, 6e94_A, 6a57_A, 5kkq_D, 2drp_D, 7txc_E, 5v3j_F, 8ssq_A, 6u9q_A, 1g2f_F, 6blw_A, 1tf6_A, 4m9v_C, 2jpa_A, 8gn3_A, 5k5i_A, 7y3m_I
Binding Motifs: UN0643.1 rGGTGAGCryGr
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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