Transcription Factor

						

			
Accessions: 5v0l_A (3D-footprint 20231221)

			
Names: ARNT protein, ARNT_HUMAN, Aryl hydrocarbon receptor nuclear translocator, bHLHe2, Class E basic helix-loop-helix protein 2, Dioxin receptor, nuclear translocator, HIF-1-beta, HIF1-beta, Hypoxia-inducible factor 1-beta
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P27540
Length: 176
Pfam Domains:     11-62 Helix-loop-helix DNA-binding domain
   74-139 PAS fold
Sequence: 
(in bold interface residues)		   1 QSSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTILRMAVSHMK   60
  61 SLKPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPQPQSEWFGSTLYDQVHP  120
 121 DDVDKLREQLSGSRRSFICRMRCEPHFVVVHCTGYDDDPEAGQGSKFCLVAIGRLQ
Interface Residues: 11, 13, 14, 15, 17, 18, 21, 22, 48
3D-footprint Homologues: 1a0a_B, 1an4_A, 5eyo_A, 1am9_A, 7ssa_L, 5nj8_D, 4zpk_A, 8osl_O, 6g1l_A, 5gnj_I, 5sy7_B, 4zpk_B, 7d8t_A, 5i50_B, 4h10_A, 7xi3_A, 5v0l_A, 4zpr_B, 7rcu_E, 4h10_B, 8osl_P, 5nj8_C, 7xhv_B, 5v0l_B, 7xi3_B
Binding Motifs: 5v0l_A wsAnC
5v0l_AB wcAGC
Binding Sites: 5v0l_C
5v0l_D
			
Publications: Seok SH, Lee W, Jiang L, Molugu K, Zheng A, Li Y, Park S, Bradfield CA, Xing Y. Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex. Proc Natl Acad Sci U S A 114:5431-5436 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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