Transcription Factor

Accessions: 1h0m_D (3D-footprint 20231221)
Names: Transcriptional activator protein TraR, TRAR_RHIRD
Organisms: Agrobacterium tumefaciens, Rhizobium radiobacter (Agrobacterium tumefaciens)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P33905
Length: 229
Pfam Domains: 20-147 Autoinducer binding domain
167-223 Bacterial regulatory proteins, luxR family
Sequence:
(in bold interface residues)
1 QHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQSTY 60
61 FDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKTA 120
121 NGFMSMFTMASDKPVIDIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEATYLRWI 180
181 AVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
Interface Residues: 186, 197, 198, 199, 201, 202, 203, 205, 206
3D-footprint Homologues: 1l3l_A, 8dq1_C, 1pp7_U, 4wuh_B
Binding Motifs: 1h0m_CD TGcdvvbntgCA
Binding Sites: 1h0m_G / 1h0m_H
Publications: Vannini A, Volpari C, Gargioli C, Muraglia E, Cortese R, De Francesco R, Neddermann P, Marco S.D. The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA. The EMBO journal 21:4393-401 (2002). [Pubmed]
Related annotations: PaperBLAST

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