Transcription Factor
| Accessions: | UP00092A (UniPROBE 20160601) |
| Names: | AI550390, c-myb, M16449, MGC18531, Myb, Myb proto-oncogene protein, myeloblastosis oncogene |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P06876 |
| Description: | myeloblastosis oncogene: Mus musculus myeloblastosis oncogene (Myb) |
| Length: | 183 |
| Pfam Domains: | 17-63 Myb-like DNA-binding domain 20-80 Myb-like DNA-binding domain 69-115 Myb-like DNA-binding domain 72-129 Myb-like DNA-binding domain 122-165 Myb-like DNA-binding domain 124-178 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 HDYDGLLPKSGKRHLGKTRWTREEDEKLKKLVEQNGTDDWKVIANYLPNRTDVQCQHRWQ 60 61 KVLNPELIKGPWTKEEDQRVIELVQKYGPKRWSVIAKHLKGRIGKQCRERWHNHLNPEVK 120 121 KTSWTEEEDRIIYQAHKRLGNRWAEIAKLLPGRTDNAIKNHWNSTMRRKVEQEGYLQEPS 180 181 KAS |
| Interface Residues: | 17, 52, 53, 54, 56, 57, 60, 61, 62, 103, 104, 105, 106, 108, 109, 113, 114, 140, 141, 150, 155, 156, 159, 160, 161, 163, 164, 165, 168 |
| 3D-footprint Homologues: | 1vfc_A, 3osg_A, 1ign_A, 1w0t_A, 5eyb_B, 7c4r_A, 7xur_A, 2kdz_A, 6kks_A, 3zqc_A, 1mse_C, 4flw_A, 2xhb_A, 7el3_B |
| Binding Motifs: | UP00092A_3 ttgawAACCGTTAwwhw UP00092A_1 wtkdmAACCGTTAwwht UP00092A_4 bsaCCAACTGcCgwk UP00092A_2 bgaccAACTGcCrysy |
| Binding Sites: | AAACCGTC AAACCGTT AAACGGTT AACCGTCA AACCGTCG AACCGTTG AACGGTCA AACGGTCG AACGGTTA AACGGTTC AACGGTTG ACCGTTAT AGCCGTTA ATCCGTTA CAACCGTC CAACGGTC CAACTGCC GACCGTTA GACGGTTA CAACCGAC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.