Transcription Factor

						

			
Accessions: HIC1_HUMAN (HOCOMOCO 10)

			
Names: Hic-1, HIC1_HUMAN, Hypermethylated in cancer 1 protein, Zinc finger and BTB domain-containing protein 29
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Uniprot: Q14526
Length: 733
Pfam Domains:    37-152 BTB/POZ domain
  440-459 C2H2-type zinc finger
  507-529 Zinc finger, C2H2 type
  507-529 C2H2-type zinc finger
  507-527 Zinc-finger of C2H2 type
  507-530 C2H2-type zinc finger
  522-546 Zinc-finger double domain
  535-558 C2H2-type zinc finger
  535-557 Zinc finger, C2H2 type
  535-557 C2H2-type zinc finger
  537-557 Zinc-finger of C2H2 type
  550-574 Zinc-finger double domain
  563-583 C2H2-type zinc finger
  563-585 Zinc finger, C2H2 type
  563-585 C2H2-type zinc finger
  578-601 Zinc-finger double domain
  590-613 C2H2-type zinc finger
  591-613 Zinc finger, C2H2 type
  591-613 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 MTFPEADILLKSGECAGQTMLDTMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRA   60
  61 HKNVLAASSAYLKSLVVHDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAP  120
 121 GAEPSLGAVLAAASYLQIPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRA  180
 181 ATPVIQACYPSPVGPPPPPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLC  240
 241 GLDLSKKSPPGSAAPERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEA  300
 301 APPSDPFRGGSGSPGPEPPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERG  360
 361 GDAAVSPGGPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYP  420
 421 CPHLAYGEPESFGDNLYVCIPCGKGFPSSEQLNAHVEAHVEEEEALYGRAEAAEVAAGAA  480
 481 GLGPPFGGGGDKVAGAPGGLGELLRPYRCASCDKSYKDPATLRQHEKTHWLTRPYPCTIC  540
 541 GKKFTQRGTMTRHMRSHLGLKPFACDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKF  600
 601 AQQRNLISHMKMHAVGGAAGAAGALAGLGGLPGVPGPDGKGKLDFPEGVFAVARLTAEQL  660
 661 SLKQQDKAAAAELLAQTTHFLHDPKVALESLYPLAKFTAELGLSPDKAAEVLSQGAHLAA  720
 721 GPDGRTIDRFSPT
Interface Residues: 423, 426, 448, 449, 450, 454, 460, 462, 463, 466, 481, 485, 487, 488, 490, 491, 494, 517, 518, 519, 520, 521, 523, 524, 526, 527, 530, 535, 545, 546, 547, 548, 549, 552, 553, 573, 574, 575, 576, 577, 578, 579, 580, 581, 583, 584, 601, 602, 603, 604, 605, 607, 608, 609, 612
3D-footprint Homologues: 5v3j_F, 7w1m_H, 1tf3_A, 8cuc_F, 7y3l_A, 2drp_D, 5k5i_A, 8ssq_A, 2gli_A, 8ssu_A, 1tf6_A, 6ml4_A, 6blw_A, 5kkq_D, 5ei9_F, 7eyi_G, 7ysf_A, 6wmi_A, 2lt7_A, 2i13_A, 6e94_A, 2jpa_A, 1ubd_C, 2kmk_A, 6jnm_A, 7n5w_A, 5und_A, 1g2f_F, 4x9j_A, 8gn3_A, 6u9q_A, 5yel_A, 1mey_C, 7txc_E, 5kl3_A, 4m9v_C, 8h9h_G, 7y3m_I, 6a57_A, 3uk3_C, 1f2i_J, 5yj3_D, 5k5l_F, 1llm_D, 2wbs_A
Binding Motifs: HIC1_HUMAN.H10MO.C|M01209 gGGkTGCCc
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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