Transcription Factor
| Accessions: | A6NHJ4 (JASPAR 2024) |
| Names: | ZN860_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A6NHJ4 |
| Length: | 632 |
| Pfam Domains: | 24-64 KRAB box 245-268 Zinc-finger double domain 258-268 C2H2-type zinc finger 273-296 Zinc-finger double domain 285-308 C2H2-type zinc finger 286-306 C2H2-type zinc finger 286-308 Zinc finger, C2H2 type 300-325 Zinc-finger double domain 313-334 C2H2-type zinc finger 314-334 Zinc-finger of C2H2 type 314-336 C2H2-type zinc finger 314-336 Zinc finger, C2H2 type 328-352 Zinc-finger double domain 341-360 C2H2-type zinc finger 342-364 Zinc finger, C2H2 type 342-362 Zinc-finger of C2H2 type 342-361 C2H2-type zinc finger 356-380 Zinc-finger double domain 369-389 C2H2-type zinc finger 370-392 Zinc finger, C2H2 type 370-392 C2H2-type zinc finger 397-409 C2H2-type zinc finger 398-420 Zinc finger, C2H2 type 398-420 C2H2-type zinc finger 416-436 Zinc-finger double domain 426-448 Zinc finger, C2H2 type 426-448 C2H2-type zinc finger 441-465 Zinc-finger double domain 453-473 C2H2-type zinc finger 454-476 Zinc finger, C2H2 type 454-476 C2H2-type zinc finger 468-493 Zinc-finger double domain 481-501 C2H2-type zinc finger 482-504 C2H2-type zinc finger 482-504 Zinc finger, C2H2 type 496-520 Zinc-finger double domain 509-525 C2H2-type zinc finger 510-530 C2H2-type zinc finger 510-532 Zinc finger, C2H2 type 525-548 Zinc-finger double domain 538-560 Zinc finger, C2H2 type 555-576 Zinc-finger double domain 586-605 Zinc-finger double domain 594-616 Zinc finger, C2H2 type 594-616 C2H2-type zinc finger 594-606 C2H2-type zinc finger 611-632 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MLREEAAQKRKEKEPGMALPQGHLTFRDVAIEFSLEEWKCLDPTQRALYRAMMLENYRNL 60 61 HSVDISSKCMMKKFSSTAQGNTEVDTGTLERHESHHIGDFCFQKIGKDIHDFEFQWQEDK 120 121 RNSHEATMTQIKKLTGSTDRYDRRHPGNKPIKDQLGLSFHSHLPELHIFQTKGKVGNQVE 180 181 KSINDASSVLTSQRISSRPKIHISNNYENNFFHSSLLTLKQEVHIREKSFQCNESGKAFN 240 241 CSSLLRKHQIIYLGGKQYKCDVCGKVFNQKRYLACHHRCHTGEKPYKCNECGKVFNQQSN 300 301 LASHHRLHTGEKPYKCEECDKVFSRKSNLERHRRIHTGEKPYKCKVCEKAFRRDSHLTQH 360 361 TRIHTGEKPYKCNECGKAFSGQSTLIHHQAIHGIGKLYKCNDCHKVFSNATTIANHWRIH 420 421 NEERSYKCNKCGKFFRRRSYLVVHWRTHTGEKPYKCNECGKTFHHNSALVIHKAIHTGEK 480 481 PYKCNECGKTFRHNSALVIHKAIHTGEKPYKCNECGKVFNQQATLARHHRLHTGEKPYKC 540 541 EECDTVFSRKSHHETHKRIHTGEKPYKCDDFDEAFSQASSYAKQRRIHMGEKHHKCDDCG 600 601 KAFTSHSHRIRHQRIHTGQKSYKCHKRGKVFS |
| Interface Residues: | 241, 243, 244, 247, 268, 269, 270, 271, 272, 275, 286, 296, 297, 298, 299, 300, 302, 303, 305, 306, 307, 309, 324, 325, 326, 327, 328, 330, 331, 334, 352, 353, 354, 355, 356, 358, 359, 381, 382, 383, 384, 386, 387, 409, 410, 411, 412, 415, 418, 436, 437, 439, 440, 443, 449, 463, 465, 467, 468, 470, 471, 475, 492, 493, 494, 495, 496, 499, 500, 520, 521, 523, 524, 525, 527, 528, 548, 549, 551, 552, 555 |
| 3D-footprint Homologues: | 2i13_A, 7w1m_H, 1tf3_A, 6jnm_A, 1tf6_A, 7eyi_G, 6a57_A, 2kmk_A, 7y3l_A, 2gli_A, 8ssu_A, 6ml4_A, 6blw_A, 5kkq_D, 6u9q_A, 5ei9_F, 1mey_C, 2drp_D, 8ssq_A, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 7n5w_A, 1g2f_F, 5k5l_F, 4x9j_A, 8gn3_A, 2wbs_A, 5kl3_A, 1f2i_J, 5und_A, 8h9h_G, 2lt7_A, 5v3j_F, 1llm_D, 5k5i_A, 6wmi_A, 5yel_A, 3uk3_C, 8cuc_F, 4m9v_C, 7txc_E, 5yj3_D |
| Binding Motifs: | UN0664.1 sykyTGCTCCCwgcy UN0664.2 TGCTCCCw |
| Binding Sites: | UN0664.1.1 UN0664.1.10 / UN0664.1.12 UN0664.1.11 / UN0664.1.14 UN0664.1.12 / UN0664.1.15 UN0664.1.13 / UN0664.1.16 UN0664.1.14 UN0664.1.15 / UN0664.1.17 UN0664.1.16 / UN0664.1.19 UN0664.1.17 / UN0664.1.20 UN0664.1.18 UN0664.1.19 UN0664.1.2 UN0664.1.20 UN0664.1.3 / UN0664.1.4 UN0664.1.4 / UN0664.1.5 UN0664.1.5 / UN0664.1.6 UN0664.1.6 / UN0664.1.7 UN0664.1.7 UN0664.1.10 / UN0664.1.8 UN0664.1.11 / UN0664.1.9 UN0664.2.7 UN0664.2.17 / UN0664.2.20 UN0664.1.13 UN0664.1.18 UN0664.1.3 UN0664.1.8 UN0664.1.9 UN0664.2.1 / UN0664.2.10 / UN0664.2.11 / UN0664.2.12 / UN0664.2.18 / UN0664.2.6 / UN0664.2.8 UN0664.2.13 / UN0664.2.15 / UN0664.2.19 / UN0664.2.2 / UN0664.2.3 / UN0664.2.9 UN0664.2.14 / UN0664.2.4 UN0664.2.16 UN0664.2.5 |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.