Transcription Factor
| Accessions: | ETV5 (HT-SELEX2 May2017) |
| Names: | ENSG00000244405, ETV5 |
| Organisms: | Homo sapiens |
| Libraries: | HT-SELEX2 May2017 1 1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Notes: | TF family: ETS experiment: HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 2, TF family: ETS experiment: Methyl-HT-SELEX Hamming distance: 2 cycle: 2 |
| Length: | 256 |
| Pfam Domains: | 21-102 Ets-domain 149-230 Ets-domain |
| Sequence: (in bold interface residues) | 1 KVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLIEPEEVARR 60 61 WGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAFPDNQRPFL 120 121 KAESECHLKVKQEPTMYREGPPYQRRGSLQLWQFLVTLLDDPANAHFIAWTGRGMEFKLI 180 181 EPEEVARRWGIQKNRPAMNYDKLSRSLRYYYEKGIMQKVAGERYVYKFVCDPDALFSMAF 240 241 PDNQRPFLKAESECHL |
| Interface Residues: | 61, 73, 74, 76, 77, 78, 80, 81, 95 |
| 3D-footprint Homologues: | 6sjf_B, 7jsa_J, 3zp5_A, 4mhg_A, 8ee9_F, 4uno_A, 2stt_A, 8smh_F, 3jtg_A, 8smj_F, 1dux_F, 1yo5_C, 4iri_A, 1awc_A, 4l18_B, 1bc8_C, 4lg0_B |
| Binding Motifs: | ETV5_3 grsCGGAwGyr ETV5_methyl_1 rrcmGGAAGtr ETV5_methyl_2 rsaGGAAGGAAGtr |
| Related annotations: | PaperBLAST |
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