Transcription Factor

Accessions: T100184_1.02 (CISBP 1.02)
Names: T100184_1.02;, unc-62
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Homeodomain
Length: 490
Pfam Domains: 336-375 Homeobox KN domain
337-375 Homeobox domain
Sequence:
(in bold interface residues)
1 MGGAPTSTPMMHHEMGEAMKRDKESIYAHPLYPLLVLLFEKCELATSTPRDTSRDGSTSS 60
61 DVCSSASFKDDLNEFVRHTQENADKQYYVPNPQLDQIMLQSIQMLRFHLLELEKVHELCD 120
121 NFCNRYVVCLKGKMPLDIVGDERASSSQPPMSPGSMGHLGHSSSPSMAGGATPMHYPPPY 180
181 EPQSVPLPENAGVMGGHPMEGSSMAYSMAGMAAAAASSSSSSNQAGDHPLANGGTLHSTA 240
241 GASQTLLPIAVSSPSTCSSGGLRQDSTPLSGETPMGHANGNSMDSISEAGDEFSVCGSND 300
301 DGRDSVLSDSANGSQNGKRKVPKVFSKEAITKFRAWLFHNLTHPYPSEEQKKQLAKETGL 360
361 TILQVNNWFINARRRIVQPMIDQNNRAGRSGQMNVCKNRRRNRSEQSPGPSPDSGSDSGA 420
421 NYSPDPSSLAASTAMPYPAEFYMQRTMPYGGFPSFTNPAMPFMNPMMGFQVAPTVDALSQ 480
481 QWVDLSAPHE
Interface Residues: 304, 317, 318, 319, 320, 321, 322, 363, 366, 367, 370, 371, 372, 373, 374, 375
3D-footprint Homologues: 5zfz_A, 2lkx_A, 6fqp_B, 3cmy_A, 1au7_A, 3d1n_M, 1zq3_P, 3rkq_B, 1puf_B, 8ik5_C, 1le8_A, 4j19_B, 7q3o_C, 8osb_E, 1mnm_C, 8bx1_A, 4xrs_G, 1k61_B, 8g87_X, 5hod_A, 6fqq_E, 1le8_B, 4xrm_B, 2d5v_B, 1fjl_B, 6a8r_A, 3lnq_A
Binding Motifs: M1123_1.02 accTgTcaw
Related annotations: PaperBLAST

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