Transcription Factor
| Accessions: | Q8N782 (JASPAR 2024) |
| Names: | ZN525_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8N782 |
| Length: | 479 |
| Pfam Domains: | 8-48 KRAB box 230-252 Zinc-finger double domain 243-252 C2H2-type zinc finger 243-263 Zinc finger, C2H2 type 243-265 C2H2-type zinc finger 258-281 Zinc-finger double domain 270-293 C2H2-type zinc finger 271-291 C2H2-type zinc finger 271-293 Zinc finger, C2H2 type 285-310 Zinc-finger double domain 298-319 C2H2-type zinc finger 299-321 Zinc finger, C2H2 type 299-321 C2H2-type zinc finger 313-337 Zinc-finger double domain 326-337 C2H2-type zinc finger 327-349 Zinc finger, C2H2 type 327-346 C2H2-type zinc finger 342-365 Zinc-finger double domain 354-377 C2H2-type zinc finger 355-377 Zinc finger, C2H2 type 355-377 C2H2-type zinc finger 369-394 Zinc-finger double domain 382-405 C2H2-type zinc finger 383-405 Zinc finger, C2H2 type 398-420 Zinc-finger double domain 410-431 C2H2-type zinc finger 411-433 C2H2-type zinc finger 411-433 Zinc finger, C2H2 type 425-449 Zinc-finger double domain 438-455 C2H2-type zinc finger 453-477 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MALPQGLLTFRDVAIEFSQEEWKCLDPAQRTLYRDVMLENYRNLVSLGISSKCTMKEFSS 60 61 TAQGNTEVIHTGTLQRHERHHIGDFSFQEIEKDIHNFEFQWQEDERNGHEAPMTKIKKLM 120 121 GSTEQYDHRHAGNKPIKYQLGSSFHSHLSELHIFQPKGKINNQVEKSINDASSVSTAQRI 180 181 SCRPKTHISNNYGDNFLNYSLLTQRQEVRMREKSFQCIESGKAFNYSSLLRKHQIIHLGE 240 241 KQYKCDVCDKVFIRKRYLARHRRCHTGEKPYKCNECGKSFSQMSSLTYHHRLHTGEKPYK 300 301 CEECDKAFRHNSALQRHRRIHTGEKPHKCNECGKTFSQKSYLACHRSIHTGKKPYECEEC 360 361 DKAFSFKSNLESHRITHTGEKPYKCNDCGKTFSHMSTLTCHRRLHTGEKPYKCEECDEAF 420 421 RFKSSLERHRRIHNGEKLYKCNECGKTFSQELSLTCHCRLHSGEKPCKCGECDKAYSFK |
| Interface Residues: | 225, 229, 253, 254, 255, 256, 257, 260, 264, 271, 282, 283, 284, 285, 287, 288, 290, 291, 294, 309, 310, 311, 312, 313, 316, 337, 338, 339, 340, 341, 343, 344, 365, 366, 367, 368, 369, 372, 374, 394, 395, 396, 397, 400, 406, 420, 421, 422, 423, 424, 425, 428, 432, 449, 450, 451, 452, 453, 456 |
| 3D-footprint Homologues: | 7w1m_H, 7n5w_A, 5v3j_F, 8ssq_A, 2drp_D, 8ssu_A, 2gli_A, 8h9h_G, 2kmk_A, 2lt7_A, 2jpa_A, 1ubd_C, 1tf3_A, 1tf6_A, 8gn3_A, 7y3m_I, 6e94_A, 8cuc_F, 7y3l_A, 7ysf_A, 7txc_E, 6u9q_A |
| Binding Motifs: | UN0201.1 AAATTGCTAATGAAGT |
| Binding Sites: | UN0201.1.1 UN0201.1.10 / UN0201.1.11 UN0201.1.11 UN0201.1.12 / UN0201.1.13 UN0201.1.13 / UN0201.1.15 UN0201.1.14 UN0201.1.15 UN0201.1.16 UN0201.1.17 UN0201.1.18 UN0201.1.19 UN0201.1.2 UN0201.1.20 UN0201.1.3 / UN0201.1.4 UN0201.1.4 / UN0201.1.5 UN0201.1.5 / UN0201.1.6 UN0201.1.6 / UN0201.1.7 UN0201.1.7 / UN0201.1.8 UN0201.1.8 UN0201.1.10 / UN0201.1.9 UN0201.1.12 UN0201.1.14 UN0201.1.18 UN0201.1.19 UN0201.1.20 UN0201.1.3 UN0201.1.9 |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.