Transcription Factor

Accessions: 1k6o_A (3D-footprint 20231221)
Names: ELK4_HUMAN, ETS domain-containing protein Elk-4, ETS-domain protein ELK-4, SAP-1, Serum response factor accessory protein 1, SRF accessory protein 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P28324
Length: 89
Pfam Domains: 3-84 Ets-domain
Sequence:
(in bold interface residues)
1 SAITLWQFLLQLLQKPQNKHMICWTSNDGQFKLLQAEEVARLWGIRKNKPNMNYDKLSRA 60
61 LRYYYVKNIIKKVNGQKFVYKFVSYPEIL
Interface Residues: 55, 56, 58, 59, 60, 62, 63, 77
3D-footprint Homologues: 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A
Binding Motifs: 1k6o_ABC AGGATnTCCATATTAGGA
Publications: Mo Y, Ho W, Johnston K, Marmorstein R. Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex. Journal of molecular biology 314:495-506 (2001). [Pubmed]
Related annotations: PaperBLAST

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