Transcription Factor

Accessions: 3qrf_G (3D-footprint 20231221)
Names: Forkhead box protein P3, FOXP3_HUMAN, Scurfin
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9BZS1
Length: 82
Pfam Domains: 2-76 Fork head domain
Sequence:
(in bold interface residues)
1 MRPPFTYATLIRWAILEAPEKQRTLNEIYHWFTRMFAFFRNHPATWKNAIRHNLSLHKCF 60
61 VRVESEKGAVWTVDELEFRKKR
Interface Residues: 42, 45, 47, 48, 49, 51, 52, 53, 55, 56, 65, 67
3D-footprint Homologues: 3l2c_A, 7vox_H, 2hdc_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7yzg_A, 7tdw_A, 3g73_A, 7yz7_A, 6el8_A, 7tdx_A, 7yzb_A, 6nce_A, 3qrf_G
Binding Motifs: 3qrf_G GAAACA
Binding Sites: 3qrf_D
3qrf_C
Publications: Bandukwala H.S, Wu Y, Feuerer M, Chen Y, Barboza B, Ghosh S, Stroud J.C, Benoist C, Mathis D, Rao A, Chen L. Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells. Immunity 34:479-91 (2011). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.