Transcription Factor
| Accessions: | T061532_1.02 (CISBP 1.02), UP00354A (UniPROBE 20160601), Q07351 (JASPAR 2024) |
| Names: | STP4, T061532_1.02;, Not Available, STP4_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p |
| Notes: | experiment type:PBM, family:C2H2 ZF |
| Length: | 490 |
| Sequence: (in bold interface residues) | 1 MLVSSSFASSIDSVMSHETMSLRRNPPFIDTPEKMPNPTASPNGTIHHLIDPSLPLLSST 60 61 TSSSRSTLSSTLNSPPPPPLTTSYSSYNSSACQSITSSPTDNTALAHNSKCYFPHSLSPT 120 121 PLSSNSSSHVILPPISSFTNLITVAEREFNGRSNSLHANFTSPVPRTVLDHHRHELTFCN 180 181 PNNTTGFKTITPSPPTQHQSILPTAVDNVPRSKSVSSLPVSGFPPLIVKQQQQQQLNSSS 240 241 SASALPSIHSPLTNEHTSRYSSSLKDSAKITKQRKKKECPICHNFYANLSTHKSTHLTPE 300 301 DRPHKCPICQRGFARNNDLIRHKKRHWKDEFMQIYARESDNNSGADDQDDTARTSANNDS 360 361 DDSNDKLAASSSSEETKLLKKNQLKSLYKIKGAFKCPYNSTLINLDMEVYPHKSRSLYFE 420 421 PINCHQTGVFSRCDTFKNHLKALHFEYPPKTKKEDRGVVPGKCKHCGLQFPNVDVWLNKH 480 481 VGKGCGYSYH |
| Interface Residues: | 260, 262, 263, 266, 286, 287, 288, 289, 290, 291, 292, 293, 294, 295, 314, 315, 316, 317, 318, 319, 320, 321, 322 |
| 3D-footprint Homologues: | 7ysf_A, 1g2f_F, 6ml4_A, 1mey_C, 4x9j_A, 2kmk_A, 5ei9_F, 7y3l_A, 3uk3_C, 4m9v_C, 6u9q_A, 7eyi_G, 2i13_A, 1llm_D, 7n5w_A, 2jpa_A, 5kl3_A, 8h9h_G, 2drp_D, 5v3j_F, 6e94_A, 8ssq_A, 8ssu_A, 5kkq_D, 7txc_E, 1f2i_J, 7w1m_H, 2wbs_A |
| Binding Motifs: | UP00354A_1 crmtsGtrCGGCTGAwvmsbm M0503_1.02 arckCTrgd MA0397.1 gmTAGCGCa MA0397.2 TAGCGC |
| Binding Sites: | ACAGCCGT ACGGCTGA AGCCGCAC AGCCGCAT AGCCGCGC AGCCGTAC AGCCGTGC ATAGCGCC CACGGCTG CAGCCGCA CAGCCGTA CGCCGCAC CGCGGCTA CGGCGCTA GCGCCGCA GCGGCTGA AAGCCGTG ACGCGGCT AGCCGTAT CTAGCGCC |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.