Transcription Factor

						

			
Accessions: UP00534A (UniPROBE 20160601)

			
Names: CG1832, Chromatin-linked adaptor for MSL proteins, CLAMP_Cterm6Zn, DMEL\CG1832
Organisms: Drosophila melanogaster
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Chromatin-linked adaptor for MSL proteins
Length: 212
Pfam Domains:     11-33 Zinc finger, C2H2 type
    11-34 C2H2-type zinc finger
    11-33 C2H2-type zinc finger
    25-49 Zinc-finger double domain
    39-61 Zinc finger, C2H2 type
    39-61 C2H2-type zinc finger
    54-77 Zinc-finger double domain
    66-77 C2H2-type zinc finger
    67-89 Zinc finger, C2H2 type
    67-89 C2H2-type zinc finger
   81-105 Zinc-finger double domain
   95-117 Zinc finger, C2H2 type
   95-115 C2H2-type zinc finger
   95-115 Zinc-finger of C2H2 type
   95-117 C2H2-type zinc finger
  110-133 Zinc-finger double domain
  122-133 C2H2-type zinc finger
  123-145 C2H2-type zinc finger
  123-145 Zinc finger, C2H2 type
  137-161 Zinc-finger double domain
  150-161 C2H2-type zinc finger
  151-170 C2H2-type zinc finger
  151-173 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 TVKTENPSKPFSCNICGGLFSRYSSLWSHKKLHSGEKNYKCSICGLAFAKAVYLKNHARI   60
  61 HTGEKPYKCQTCGMQFSQSPHLKNHERTHSGERPYVCGVCDKGFARHATLWNHRRIHTGE  120
 121 KPYKCEICGSAFSQAAHLKNHAKVHSGEKPYKCEICSAAFADRFALKRHRGIHQKYGQTA  180
 181 PRQTSSDGMIVHKQEIPDMEDEAQQEVIIGGL
Interface Residues: 11, 22, 23, 24, 25, 27, 28, 30, 31, 34, 49, 50, 51, 52, 53, 55, 56, 77, 78, 79, 80, 81, 83, 84, 103, 105, 106, 107, 108, 109, 110, 112, 113, 115, 119, 120, 133, 134, 135, 136, 137, 138, 139, 140, 141, 144, 162, 163, 164, 165, 167, 168
3D-footprint Homologues: 2kmk_A, 5yel_A, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 5v3j_F, 2i13_A, 2jpa_A, 1ubd_C, 1tf3_A, 3uk3_C, 6jnm_A, 7n5w_A, 5ei9_F, 5kl3_A, 6wmi_A, 5k5i_A, 1tf6_A, 8h9h_G, 7eyi_G, 6e94_A, 7ysf_A, 2lt7_A, 8cuc_F, 5kkq_D, 6ml4_A, 1mey_C, 6blw_A, 2drp_D, 2wbs_A, 1f2i_J, 6u9q_A, 7txc_E, 1g2f_F, 2gli_A, 4x9j_A, 4m9v_C, 7y3m_I, 6a57_A, 8gn3_A, 1yuj_A, 7y3l_A, 1llm_D, 5k5l_F, 5yj3_D
Binding Motifs: UP00534A_1 / UP00534A_2 tvktgwgAGAGAGAGAvarwmkr
UP00534A_3 gymkgrGTGArAmGGAmgryymm
Binding Sites: AAAAGAGA
AAAGAGAA
ACTATCTC
ACTCTTCT
AGAAAGAG
AGAGAGAG
AGAGATAG
AGAGCAGG
CTGTCTCA
GAAAAGGA
GAAAGAGA
GAAAGGGA
GACAGAGA
GAGAAAGA
GAGACAGA
GAGACGGA
GAGAGAGA
GAGAGGGA
GAGCGAGA
GAGTGAGA
			
Publications: Soruco MM, Chery J, Bishop EP, Siggers T, Tolstorukov MY, Leydon AR, Sugden AU, Goebel K, Feng J, Xia P, Vedenko A, Bulyk ML, Park PJ, Larschan E. The CLAMP protein links the MSL complex to the X chromosome during Drosophila dosage compensation. Genes Dev 27:1551-6 (2013). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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