Transcription Factor

Accessions: UP00091A (UniPROBE 20160601)
Names: AI528773, MGC124352, Sox-5, Sox5, SRY-box containing gene 5, Transcription factor SOX-5
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P35710
Description: SRY-box containing gene 5
Length: 101
Pfam Domains: 17-85 HMG (high mobility group) box
18-78 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 SRIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTN 60
61 LEKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKL
Interface Residues: 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86
3D-footprint Homologues: 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 1hry_A
Binding Motifs: UP00091A_1 wwdrgAACAATwaahw
UP00091A_2 wwtCatmAttwasdd
Binding Sites: AAACAATT
AAATTGTT
AACAATAA
AACAATAG
AACAATGG
AACAATTA
AACAATTG
AAGACAAT
AATTGTTA
ACAACAAT
ACAATTGT
AGAACAAT
AGACAATA
ATTGTTAA
ATTGTTCA
ATTGTTCG
ATTGTTTC
CAATTGTC
GAACAATA
TAACAATA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.