Transcription Factor

Accessions: UP00410A (UniPROBE 20160601)
Names: Elk-1, Elk1, ETS domain-containing protein Elk-1, member of ETS oncogene family
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P41969
Description: ELK1, member of ETS oncogene family : ETS domain-containing protein Elk-1
Length: 104
Pfam Domains: 4-86 Ets-domain
Sequence:
(in bold interface residues)
1 DPSVTLWQFLLQLLREQGNGHIISWTSRDGGEFKLVDAEEVARLWGLRKNKTNMNYDKLS 60
61 RALRYYYDKNIIRKVSGQKFVYKFVSYPEVAGCSTEDCPPQPEV
Interface Residues: 57, 58, 60, 61, 62, 64, 65, 79
3D-footprint Homologues: 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C
Binding Motifs: UP00410A_1 mswtACCGGAAGYdsmr
Binding Sites: AACCGGAA
AACTTCCG
ACATCCGG
ACCGGAAA
ACCGGAAC
ACTTCCGC
ACTTCCGG
AGTTCCGG
ATTTCCGG
CACCGGAA
CACTTCCG
CCGGAAAC
CCGGAAGC
CGGAAGTA
CGGAAGTC
CTTCCGGA
CTTCCGGC
GACCGGAA
TACCGGAA
TTCCGGAA
Publications: Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.