Transcription Factor

Accessions: Q16665 (JASPAR 2024)
Names: ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, bHLHe78, Class E basic helix-loop-helix protein 78, HIF-1-alpha, HIF1-alpha, HIF1A_HUMAN, Hypoxia-inducible factor 1-alpha, Member of PAS protein 1, PAS domain-containing protein 8
Organisms: Homo sapiens, Oryctolagus cuniculus, Rattus rattus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q16665
Length:
Binding Motifs: MA0259.1 vbACGTGc
MA1106.1 gbACGTGCss
MA0259.2 ACGTG
MA1106.2 ACGTGC
Binding Sites: MA0259.1.1
MA0259.1.10
MA0259.1.11
MA0259.1.12
MA0259.1.13
MA0259.1.14
MA0259.1.15
MA0259.1.16
MA0259.1.17
MA0259.1.18
MA0259.1.19
MA0259.1.2
MA0259.1.20
MA0259.1.3
MA0259.1.4
MA0259.1.5
MA0259.1.6
MA0259.1.7
MA0259.1.8
MA0259.1.9
MA1106.1.1
MA1106.1.10
MA1106.1.11
MA1106.1.12
MA1106.1.13
MA1106.1.14
MA1106.1.15
MA1106.1.16
MA1106.1.17
MA1106.1.18 / MA1106.1.4
MA1106.1.19
MA1106.1.2
MA1106.1.20
MA1106.1.3
MA1106.1.5
MA1106.1.6
MA1106.1.7
MA1106.1.8
MA1106.1.9
MA0259.2.1 / MA0259.2.10
MA0259.2.11 / MA0259.2.4 / MA0259.2.5 / MA0259.2.8 / MA0259.2.9
MA0259.2.12
MA0259.2.13 / MA0259.2.16
MA0259.2.14 / MA0259.2.18
MA0259.2.15
MA0259.2.17 / MA0259.2.20
MA0259.2.19
MA0259.2.2 / MA0259.2.3
MA0259.2.6
MA0259.2.7
MA1106.2.1 / MA1106.2.12 / MA1106.2.13 / MA1106.2.14 / MA1106.2.15 / MA1106.2.16 / MA1106.2.19 / MA1106.2.20 / MA1106.2.3 / MA1106.2.5 / MA1106.2.6 / MA1106.2.7 / MA1106.2.8 / MA1106.2.9
MA1106.2.10 / MA1106.2.17 / MA1106.2.2
MA1106.2.11 / MA1106.2.18 / MA1106.2.4
Publications: Wenger R.H, Stiehl D.P, Camenisch G. Integration of oxygen signaling at the consensus HRE. Science's STKE : signal transduction knowledge environment 2005:re12 (2005). [Pubmed]

Ortiz-Barahona A, Villar D, Pescador N, Amigo J, del Peso L. Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Nucleic Acids Res 38:2332-45 (2010). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.