Transcription Factor

Accessions: T057650_1.02 (CISBP 1.02)
Names: lsy-2, T057650_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 339
Pfam Domains: 51-70 C2H2-type zinc finger
52-70 C2H2-type zinc finger
67-89 Zinc-finger double domain
80-102 Zinc finger, C2H2 type
80-102 C2H2-type zinc finger
80-102 C2H2-type zinc finger
94-117 Zinc-finger double domain
108-130 C2H2-type zinc finger
108-130 Zinc finger, C2H2 type
238-249 C2H2-type zinc finger
270-292 Zinc finger, C2H2 type
270-292 C2H2-type zinc finger
271-292 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MTHGSNQSVYHHNQHMDDSEMMMDEQDYSQYQMGFPEEDEMVEGMMTPRAVHQCNVCNKI 60
61 FVSYKGLQQHAVIHTDQKPFRCDICSKSFRFKSNLFEHRSVHTGFTPHACPYCGKTCRLK 120
121 GNLKKHLRTHVTTKEELEAAWRPFASNRRPPADIPDDAIVLRGAGGPYYTPPPRPKKKKL 180
181 GLGEPEHWVDKLRRGDLLPQVELEDKIRRLEDTIFNNMSLERWGNLFEIAKSIAFETHDC 240
241 PVCKSQFMTRMDCVSHHTLEHENHREGLEFFCEKCYRPFADEASYNQHMSYHTRVSSLIE 300
301 TGEIVPQPADPEILVPTNDEFQMLFGANFGQQMMEPQLI
Interface Residues: 43, 62, 63, 64, 65, 66, 68, 69, 71, 72, 73, 75, 90, 91, 92, 93, 94, 96, 97, 98, 118, 119, 120, 121, 122, 123, 124, 125, 126, 129
3D-footprint Homologues: 1ubd_C, 7n5w_A, 6jnm_A, 6ml4_A, 3uk3_C, 8cuc_F, 7y3l_A, 8gn3_A, 4x9j_A, 2gli_A, 1f2i_J, 5kl3_A, 5ei9_F, 1g2f_F, 7ysf_A, 7w1m_H, 6blw_A, 5k5i_A, 2kmk_A, 1llm_D, 5kkq_D, 8h9h_G, 7y3m_I, 6e94_A, 2lt7_A, 6a57_A, 2jpa_A, 5yj3_D, 2wbs_A, 1tf6_A, 7txc_E, 5v3j_F, 8ssq_A, 6u9q_A, 5yel_A, 2drp_D, 4m9v_C, 1tf3_A
Binding Motifs: M0453_1.02 rwTACkGTAg
Related annotations: PaperBLAST

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