Transcription Factor
| Accessions: | O75123 (JASPAR 2024) |
| Names: | ZN623_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | O75123 |
| Length: | 536 |
| Pfam Domains: | 124-145 C2H2-type zinc finger 125-145 Zinc finger, C2H2 type 125-145 C2H2-type zinc finger 137-161 Zinc-finger double domain 150-171 C2H2-type zinc finger 151-173 Zinc finger, C2H2 type 151-173 C2H2-type zinc finger 165-188 Zinc-finger double domain 178-202 C2H2-type zinc finger 179-201 Zinc finger, C2H2 type 179-201 C2H2-type zinc finger 194-216 Zinc-finger double domain 207-229 C2H2-type zinc finger 207-229 Zinc finger, C2H2 type 207-229 C2H2-type zinc finger 222-245 Zinc-finger double domain 234-255 C2H2-type zinc finger 235-257 Zinc finger, C2H2 type 235-257 C2H2-type zinc finger 250-272 Zinc-finger double domain 262-277 C2H2-type zinc finger 263-285 C2H2-type zinc finger 263-285 Zinc finger, C2H2 type 278-302 Zinc-finger double domain 291-313 C2H2-type zinc finger 291-311 C2H2-type zinc finger 291-313 Zinc finger, C2H2 type 306-328 Zinc-finger double domain 319-341 Zinc finger, C2H2 type 319-341 C2H2-type zinc finger 319-339 C2H2-type zinc finger 336-357 Zinc-finger double domain 347-369 Zinc finger, C2H2 type 347-369 C2H2-type zinc finger 347-367 C2H2-type zinc finger 361-384 Zinc-finger double domain 374-389 C2H2-type zinc finger 375-397 Zinc finger, C2H2 type 375-397 C2H2-type zinc finger 390-413 Zinc-finger double domain 402-412 C2H2-type zinc finger 403-425 Zinc finger, C2H2 type 403-425 C2H2-type zinc finger 417-440 Zinc-finger double domain 430-443 C2H2-type zinc finger 431-453 Zinc finger, C2H2 type 447-468 Zinc-finger double domain 459-479 C2H2-type zinc finger 459-481 Zinc finger, C2H2 type 459-481 C2H2-type zinc finger 473-497 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MILLSFVSDSNVGTGEKKVTEAWISEDENSHRTTSDRLTVMELPSPESEEVHEPRLGELL 60 61 GNPEGQSLGSSPSQDRGCKQVTVTHWKIQTGETAQVCTKSGRNHILNSDLLLLQRELIEG 120 121 EANPCDICGKTFTFNSDLVRHRISHAGEKPYTCDQCGKGFGQSSHLMEHQRIHTGERLYV 180 181 CNVCGKDFIHYSGLIEHQRVHSGEKPFKCAQCGKAFCHSSDLIRHQRVHTRERPFECKEC 240 241 GKGFSQSSLLIRHQRIHTGERPYECNECGKSFIRSSSLIRHYQIHTEVKQYECKECGKAF 300 301 RHRSDLIEHQRIHTGERPFECNECGKAFIRSSKLIQHQRIHTGERPYVCNECGKRFSQTS 360 361 NFTQHQRIHTGEKLYECNECGKAFFLSSYLIRHQKIHTGERVYECKECGKAFLQKAHLTE 420 421 HQKIHSGDRPFECKDCGKAFIQSSKLLLHQIIHTGEKPYVCSYCGKGFIQRSNFLQHQKI 480 481 HTEEKLYECSQYGRDFNSTTNVKNNQRVHQEGLSLSKAPIHLGERSVDKGEHTGNL |
| Interface Residues: | 134, 136, 137, 140, 161, 162, 163, 164, 165, 168, 189, 190, 191, 192, 193, 195, 196, 198, 199, 200, 202, 217, 218, 219, 220, 221, 224, 245, 246, 247, 248, 249, 251, 252, 253, 263, 274, 275, 276, 277, 278, 279, 280, 281, 284, 301, 302, 303, 304, 305, 308, 311, 329, 330, 331, 332, 333, 336, 342, 356, 357, 358, 359, 360, 361, 362, 363, 364, 367, 368, 385, 386, 387, 388, 389, 391, 392, 413, 414, 415, 416, 417, 442, 444, 445, 448 |
| 3D-footprint Homologues: | 7w1m_H, 6u9q_A, 7ysf_A, 5ei9_F, 6wmi_A, 1g2f_F, 8ssq_A, 6ml4_A, 5kkq_D, 2jpa_A, 1mey_C, 5kl3_A, 5und_A, 1tf6_A, 4x9j_A, 3uk3_C, 8cuc_F, 1f2i_J, 5k5i_A, 5v3j_F, 1llm_D, 4m9v_C, 5yel_A, 2kmk_A, 2drp_D, 5yj3_D, 8ssu_A, 2i13_A, 1ubd_C, 1tf3_A, 6jnm_A, 7y3l_A, 7n5w_A, 2gli_A, 8gn3_A, 8h9h_G, 7eyi_G, 6a57_A, 7txc_E, 6blw_A, 6e94_A, 7y3m_I, 2wbs_A, 2lt7_A, 5k5l_F |
| Binding Motifs: | UN0210.1 awGTGCAAAGGCCCTGrGGyaG UN0210.2 GTGCAAAGGCCCTGrGGyaG |
| Binding Sites: | UN0210.1.1 UN0210.1.10 UN0210.1.11 UN0210.1.12 UN0210.1.13 UN0210.1.14 UN0210.1.15 UN0210.1.16 UN0210.1.17 UN0210.1.18 UN0210.1.19 UN0210.1.2 UN0210.1.20 UN0210.1.3 UN0210.1.4 UN0210.1.5 UN0210.1.6 UN0210.1.7 UN0210.1.8 UN0210.1.9 UN0210.2.1 / UN0210.2.5 UN0210.2.10 / UN0210.2.3 / UN0210.2.6 UN0210.2.11 UN0210.2.12 UN0210.2.13 / UN0210.2.17 / UN0210.2.4 / UN0210.2.8 UN0210.2.14 UN0210.2.15 UN0210.2.16 UN0210.2.18 UN0210.2.19 UN0210.2.2 UN0210.2.20 / UN0210.2.7 UN0210.2.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.