Transcription Factor

						

			
Accessions: E2F3_DBD (HumanTF 1.0)

			
Names: E2F-3, E2F3, E2F3_HUMAN, Transcription factor E2F3
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: O00716
Notes: Ensembl ID: ENSG00000112242; DNA-binding domain sequence; TF family: E2F; Clone source: Megaman
Length: 111
Pfam Domains:     26-91 E2F/DP family winged-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MAGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLNKAAEVLK   60
  61 VQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQCQGLSKEV
Interface Residues: 26, 62, 63, 64, 65, 67
3D-footprint Homologues: 4yo2_A, 1cf7_A, 1cf7_B
Binding Motifs: E2F3_DBD_1 aAAAAkGGCGCCAAAAtk
E2F3_DBD_2 aAAAAkGGCGCCawWTTt
E2F3_DBD_3 adTTTTGGCGCCAAAAct
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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