Transcription Factor

Accessions: 5sy7_B (3D-footprint 20231221)
Names: Basic-helix-loop-helix-PAS protein MOP6, Member of PAS protein 6, Neuronal PAS domain-containing protein 3, Neuronal PAS3, NPAS3_MOUSE
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q9QZQ0
Length: 276
Pfam Domains: 70-130 PAS fold
179-252 PAS fold
Sequence:
(in bold interface residues)
1 RKEKSRDAARSRRGKENFEFYELAKLLPLPAAITSQLDKASIIRLTISYLKMRDFANQGD 60
61 IEVFEAHLGSHILQSLDGFVFALNQEGKFLYISETVSIYLGLSQVELTGSSVFDYVHPGD 120
121 HVEMAEQLGMLERSFFIRMKSTLGYKVIHITGRLRMGLVVVAHALPHMFVTRVNMDLNII 180
181 YCENRISDYMDLTPVDIVGKRCYHFIHAEDVEGIRHSHLDLLNKGQCVTKYYRWMQKNGG 240
241 YIWIQSSATIAKNIIWVNYLLSNPEYKDTPMDIAQL
Interface Residues: 1, 2, 5, 6, 8, 9, 12, 13, 39
3D-footprint Homologues: 4zpr_B, 1a0a_B, 4h10_A, 7xi3_B, 7ssa_L, 4zpk_A, 5sy7_B, 7xhv_B, 4zpk_B, 5v0l_A, 7xi3_A, 8osl_P, 5nj8_C, 5v0l_B
Binding Motifs: 5sy7_AB aCGTGCg
Binding Sites: 5sy7_C
5sy7_D
Publications: Wu D, Su X, Potluri N, Kim Y, Rastinejad F. NPAS1-ARNT and NPAS3-ARNT crystal structures implicate the bHLH-PAS family as multi-ligand binding transcription factors. Elife : (2016). [Pubmed]
Related annotations: PaperBLAST

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