Transcription Factor

Accessions: 4mhg_A (3D-footprint 20231221)
Names: ETS translocation variant 6, ETS-related protein Tel1, ETV6_MOUSE, Transcription factor ETV6
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P97360
Length: 90
Pfam Domains: 2-83 Ets-domain
Sequence:
(in bold interface residues)
1 RLLWDYVYQLLSDSRYENFIRWEDKESKIFRIVDPNGLARLWGNHKNRTNMTYEKMSRAL 60
61 RHYYKLNIIRKEPGQRLLFRFMKTPDEIMS
Interface Residues: 54, 55, 57, 58, 59, 61, 62, 76
3D-footprint Homologues: 4uno_A, 3jtg_A, 1dux_F, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 4iri_A, 1bc8_C, 4l18_B, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A
Binding Motifs: 4mhg_A anCCGGAA
Binding Sites: 4mhg_B
4mhg_C
Publications: De S, Chan A.C, Coyne H.J, Bhachech N, Hermsdorf U, Okon M, Murphy M.E, Graves B.J, McIntosh L.P. Steric mechanism of auto-inhibitory regulation of specific and non-specific DNA binding by the ETS transcriptional repressor ETV6. Journal of molecular biology 426:1390-406 (2014). [Pubmed]
Related annotations: PaperBLAST

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