Transcription Factor
| Accessions: | Q9H8G1 (JASPAR 2024) |
| Names: | ZN430_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q9H8G1 |
| Length: | 570 |
| Pfam Domains: | 35-74 KRAB box 198-214 Zinc-finger double domain 205-225 C2H2-type zinc finger 219-243 Zinc-finger double domain 233-255 Zinc finger, C2H2 type 233-255 C2H2-type zinc finger 233-253 C2H2-type zinc finger 248-272 Zinc-finger double domain 260-280 C2H2-type zinc finger 261-283 Zinc finger, C2H2 type 261-283 C2H2-type zinc finger 276-299 Zinc-finger double domain 289-311 Zinc finger, C2H2 type 289-311 C2H2-type zinc finger 289-309 C2H2-type zinc finger 303-327 Zinc-finger double domain 317-339 Zinc finger, C2H2 type 317-339 C2H2-type zinc finger 317-336 C2H2-type zinc finger 331-355 Zinc-finger double domain 344-364 C2H2-type zinc finger 345-367 Zinc finger, C2H2 type 345-366 C2H2-type zinc finger 360-383 Zinc-finger double domain 372-392 C2H2-type zinc finger 373-395 Zinc finger, C2H2 type 373-395 C2H2-type zinc finger 388-411 Zinc-finger double domain 401-421 C2H2-type zinc finger 401-423 Zinc finger, C2H2 type 401-423 C2H2-type zinc finger 416-439 Zinc-finger double domain 428-448 C2H2-type zinc finger 429-451 Zinc finger, C2H2 type 429-451 C2H2-type zinc finger 443-467 Zinc-finger double domain 456-476 C2H2-type zinc finger 457-479 Zinc finger, C2H2 type 457-476 C2H2-type zinc finger 472-495 Zinc-finger double domain 484-507 C2H2-type zinc finger 485-507 Zinc finger, C2H2 type 485-507 C2H2-type zinc finger 499-523 Zinc-finger double domain 528-551 Zinc-finger double domain |
| Sequence: (in bold interface residues) | 1 MENLKSGVYPLKEASGCPGADRNLLVYSFYEKGPLTFRDVAIEFSLEEWQCLDTAQQDLY 60 61 RKVMLENYRNLVFLAGIAVSKPDLITCLEQGKEPWNMKRHAMVDQPPVTYSHFAQDLWPE 120 121 QGIKDSFQEVILRRYGKCGHEDLQLRTGCKSVDECNLHKECYDELNQCLTTTQSEIFQYD 180 181 KYVNVFYKFSNPNIQKIRHTGKKPFKCKKCDKSFCMLLHLTQHKRIHIRENSYQCEECGK 240 241 VFNWFSTLTRHRRIHTGEKPYKCEQCGKAFKQSSTLTTHKIIHTGEKPYRCEECGKTFNR 300 301 SSHLTTHKRIHTGEKPYRCEECGRAFNRSSHLTTHKIIHTGEKPYKCEECGKAFNQSSTL 360 361 TTHKIIHAGEKPYKCEECGKAFYRFSYLTKHKIIHTGEKFYKCEECGKGFNWSSTLTKHK 420 421 RIHTGEKPYKCEQCGKAFNESSNLTAHKIIHTGEKPYKCEECGKAFNRSPKLTAHKVIHS 480 481 GEKPYKCEECGKAFNQFSNLTKHKITHIGDTSYKYLECDKAFSQSSTLTKHKVIHTGEKP 540 541 YNCEEYGKAFNQSSNLIEQSNSYWRETLQM |
| Interface Residues: | 216, 218, 219, 243, 244, 245, 246, 247, 250, 261, 271, 272, 273, 274, 275, 277, 278, 279, 280, 281, 282, 284, 299, 300, 301, 302, 303, 304, 306, 307, 310, 327, 328, 329, 330, 331, 333, 334, 355, 356, 357, 358, 359, 361, 362, 383, 384, 385, 386, 387, 390, 411, 412, 413, 414, 415, 417, 418, 421, 422, 440, 441, 442, 443, 445, 446, 452, 466, 467, 468, 469, 470, 471, 472, 474, 478, 495, 496, 497, 498, 499, 502, 523, 524, 526, 527, 530 |
| 3D-footprint Homologues: | 2i13_A, 3uk3_C, 7n5w_A, 5k5i_A, 6wmi_A, 7w1m_H, 7eyi_G, 8h9h_G, 2kmk_A, 8ssu_A, 2gli_A, 8gn3_A, 6blw_A, 8ssq_A, 1mey_C, 4m9v_C, 7ysf_A, 2jpa_A, 7y3l_A, 5und_A, 1f2i_J, 5v3j_F, 1g2f_F, 4x9j_A, 1llm_D, 7txc_E, 5kl3_A, 2wbs_A, 5ei9_F, 5yj3_D, 1tf6_A, 5yel_A, 6jnm_A, 6ml4_A, 6a57_A, 8cuc_F, 5kkq_D, 2lt7_A, 7y3m_I, 6e94_A, 1ubd_C, 2drp_D, 6u9q_A, 1tf3_A |
| Binding Motifs: | UN0188.1 AgGcCTCACAATCATGGmAKrARg |
| Binding Sites: | UN0188.1.1 / UN0188.1.2 UN0188.1.10 / UN0188.1.9 UN0188.1.10 / UN0188.1.11 UN0188.1.11 / UN0188.1.12 UN0188.1.13 UN0188.1.14 UN0188.1.15 UN0188.1.16 UN0188.1.14 / UN0188.1.17 / UN0188.1.18 UN0188.1.15 / UN0188.1.18 UN0188.1.16 / UN0188.1.19 UN0188.1.20 UN0188.1.3 UN0188.1.4 UN0188.1.5 / UN0188.1.6 UN0188.1.6 UN0188.1.7 UN0188.1.8 UN0188.1.9 UN0188.1.12 UN0188.1.13 UN0188.1.17 UN0188.1.19 UN0188.1.20 UN0188.1.4 UN0188.1.5 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.