Transcription Factor

Accessions: 2d45_A (3D-footprint 20231221), 2d45_C (3D-footprint 20231221)
Names: MECI_STAAN, Methicillin resistance regulatory protein mecI
Organisms: Staphylococcus aureus, strain N315
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P68261
Length: 117
Pfam Domains: 4-117 Penicillinase repressor
4-60 MarR family
Sequence:
(in bold interface residues)
1 TYEISSAEWEVMNIIWMKKYASANNIIEEIQMQKDWSPKTIRTLITRLYKKGFIDRKKDN 60
61 KIFQYYSLVEESDIKYKTSKNFINKVYKGGFNSLVLNFVEKEDLSQDEIEELRNILN
Interface Residues: 23, 39, 40, 42, 43, 44, 46, 47, 51, 63, 65
3D-footprint Homologues: 2p7c_B, 1xsd_A, 1sax_A
Binding Motifs: 2d45_AB TanTACATATGTA
2d45_CD ACAnnTGTAgTA
Publications: Safo M.K, Ko T.P, Musayev F.N, Zhao Q, Wang A.H, Archer G.L. Structure of the MecI repressor from Staphylococcus aureus in complex with the cognate DNA operator of mec. Acta crystallographica. Section F, Structural biology and crystallization communications 62:320-4 (2006). [Pubmed]
Related annotations: PaperBLAST

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