Transcription Factor

Accessions: B2RUK9 (JASPAR 2024)
Names: B2RUK9_MOUSE
Organisms: Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: B2RUK9
Length: 458
Pfam Domains: 3-42 KRAB box
98-114 Zinc-finger double domain
105-128 C2H2-type zinc finger
106-128 Zinc finger, C2H2 type
121-145 Zinc-finger double domain
133-149 C2H2-type zinc finger
134-149 C2H2-type zinc finger
134-149 Zinc finger, C2H2 type
153-173 Zinc-finger double domain
161-180 C2H2-type zinc finger
162-184 C2H2-type zinc finger
162-184 Zinc finger, C2H2 type
177-199 Zinc-finger double domain
190-212 Zinc finger, C2H2 type
239-257 Zinc-finger double domain
245-268 C2H2-type zinc finger
246-268 Zinc finger, C2H2 type
261-285 Zinc-finger double domain
274-296 Zinc finger, C2H2 type
274-296 C2H2-type zinc finger
289-311 Zinc-finger double domain
301-325 C2H2-type zinc finger
302-324 Zinc finger, C2H2 type
302-324 C2H2-type zinc finger
316-341 Zinc-finger double domain
329-349 C2H2-type zinc finger
330-352 Zinc finger, C2H2 type
330-352 C2H2-type zinc finger
344-368 Zinc-finger double domain
357-380 C2H2-type zinc finger
358-380 C2H2-type zinc finger
358-380 Zinc finger, C2H2 type
372-397 Zinc-finger double domain
386-408 C2H2-type zinc finger
386-408 Zinc finger, C2H2 type
402-425 Zinc-finger double domain
413-436 C2H2-type zinc finger
414-436 C2H2-type zinc finger
414-436 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MLSFWDVAIDFSPEEWDCLEPAQWDLYRNVMLENFSHLVFLGLAVSKPFLVTFLEQRQGP 60
61 WDMKRQGMATVYPGIKPNDPNNFSKLTNCKSLLITQRRNHIGEKPYKCGECGKALSSHKT 120
121 LSIHQRLHTGDKPYKCEECHKAFSTRSSLFIYMKNHTDEKIYKCEDCGRTFYYLSMLKQH 180
181 QRIHSGEKPYKCEECGKCFGFPSFLKQHQNIHCRKNAYTYEDCVKRLSPPLPLQDNEQIH 240
241 TEEKPYKCGECYKAFSYHSAFRIHKTVHTGENPYKCEECGKCFSSSSYLKRHQTLHSEDK 300
301 PYKCEDCGRCFCSSSSLRRHQKFHSEGNPYKCEKCDKRFSCSASLQEHQTIHTGEKPYTC 360
361 ENCHKAFRYRSSLRKHKTVHTREKSYNCKKCPRAFSSYSCFVRHQAIHSEDNPHKCVECG 420
421 KAFVNVYSLTRHMTVHAGEKSYKGLKTLILLQSLKDIK
Interface Residues: 97, 99, 100, 116, 117, 118, 119, 120, 123, 127, 144, 145, 146, 147, 148, 150, 151, 155, 172, 173, 174, 175, 176, 178, 179, 180, 201, 202, 203, 204, 205, 206, 207, 208, 211, 227, 229, 230, 231, 232, 233, 235, 256, 257, 258, 259, 260, 263, 285, 286, 287, 288, 290, 291, 293, 294, 295, 297, 302, 312, 313, 314, 315, 316, 319, 322, 340, 341, 342, 343, 344, 347, 369, 370, 371, 372, 374, 375, 381, 395, 397, 398, 399, 400, 401, 402, 403, 407, 424, 425, 426, 427, 428
3D-footprint Homologues: 2i13_A, 7y3l_A, 7n5w_A, 3uk3_C, 6jnm_A, 8cuc_F, 4x9j_A, 6u9q_A, 5ei9_F, 5k5i_A, 8ssq_A, 1g2f_F, 8ssu_A, 8h9h_G, 7eyi_G, 7y3m_I, 6ml4_A, 7w1m_H, 5k5l_F, 5v3j_F, 4m9v_C, 5yj3_D, 6wmi_A, 1tf3_A, 1tf6_A, 8gn3_A, 1llm_D, 1mey_C, 5und_A, 2gli_A, 1ubd_C, 6blw_A, 5kkq_D, 6e94_A, 7ysf_A, 5yel_A, 6a57_A, 2jpa_A, 2kmk_A, 2wbs_A, 7txc_E, 5kl3_A, 1f2i_J, 2lt7_A, 2drp_D
Binding Motifs: UN0678.1 trwkCAGGGTCCTdsv
UN0678.2 kCAGGGTCCT
Binding Sites: UN0678.1.1 / UN0678.1.2
UN0678.1.10 / UN0678.1.11
UN0678.1.11 / UN0678.1.13
UN0678.1.12 / UN0678.1.16
UN0678.1.13 / UN0678.1.17
UN0678.1.14 / UN0678.1.19
UN0678.1.15
UN0678.1.16
UN0678.1.17
UN0678.1.18
UN0678.1.19
UN0678.1.2 / UN0678.1.3
UN0678.1.20
UN0678.1.3 / UN0678.1.4
UN0678.1.4 / UN0678.1.5
UN0678.1.5 / UN0678.1.6
UN0678.1.6 / UN0678.1.7
UN0678.1.7 / UN0678.1.8
UN0678.1.8 / UN0678.1.9
UN0678.1.10 / UN0678.1.9
UN0678.1.1
UN0678.1.12
UN0678.1.14
UN0678.1.15
UN0678.1.18
UN0678.1.20
UN0678.2.1 / UN0678.2.13 / UN0678.2.4 / UN0678.2.8
UN0678.2.10 / UN0678.2.11 / UN0678.2.14 / UN0678.2.17 / UN0678.2.5
UN0678.2.12
UN0678.2.15
UN0678.2.16
UN0678.2.18
UN0678.2.19
UN0678.2.2
UN0678.2.20
UN0678.2.3
UN0678.2.6
UN0678.2.7
UN0678.2.9
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.