Transcription Factor

Accessions: 4y60_C (3D-footprint 20231221)
Names: SOX18_MOUSE, Transcription factor SOX-18
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P43680
Length: 76
Pfam Domains: 4-72 HMG (high mobility group) box
5-65 Domain of unknown function (DUF1898)
Sequence:
(in bold interface residues)
1 GLRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNTAEKRPFVEEAERL 60
61 RVQHLRDHPNYKYRPR
Interface Residues: 6, 9, 11, 12, 15, 19, 30, 31, 32, 35, 73
3D-footprint Homologues: 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B
Binding Motifs: 4y60_C ACAATg
Binding Sites: 4y60_A
4y60_B
Publications: Klaus M, Prokoph N, Girbig M, Wang X, Huang YH, Srivastava Y, Hou L, Narasimhan K, Kolatkar PR, Francois M, Jauch R. Structure and decoy-mediated inhibition of the SOX18/Prox1-DNA interaction. Nucleic Acids Res 44:3922-35 (2016). [Pubmed]
Related annotations: PaperBLAST

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