Transcription Factor
| Accessions: | INSM1_HUMAN (HOCOMOCO 10), Q01101 (JASPAR 2024) |
| Names: | INSM1_HUMAN, Insulinoma-associated protein 1, Zinc finger protein IA-1 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 510 |
| Pfam Domains: | 295-317 C2H2-type zinc finger 295-317 Zinc finger, C2H2 type 367-390 C2H2-type zinc finger 367-389 Zinc finger, C2H2 type 442-464 C2H2-type zinc finger 443-464 Zinc finger, C2H2 type 469-492 C2H2-type zinc finger 469-492 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MPRGFLVKRSKKSTPVSYRVRGGEDGDRALLLSPSCGGARAEPPAPSPVPGPLPPPPPAE 60 61 RAHAALAAALACAPGPQPPPQGPRAAHFGNPEAAHPAPLYSPTRPVSREHEKHKYFERSF 120 121 NLGSPVSAESFPTPAALLGGGGGGGASGAGGGGTCGGDPLLFAPAELKMGTAFSAGAEAA 180 181 RGPGPGPPLPPAAALRPPGKRPPPPTAAEPPAKAVKAPGAKKPKAIRKLHFEDEVTTSPV 240 241 LGLKIKEGPVEAPRGRAGGAARPLGEFICQLCKEEYADPFALAQHKCSRIVRVEYRCPEC 300 301 AKVFSCPANLASHRRWHKPRPAPAAARAPEPEAAARAEAREAPGGGSDRDTPSPGGVSES 360 361 GSEDGLYECHHCAKKFRRQAYLRKHLLAHHQALQAKGAPLAPPAEDLLALYPGPDEKAPQ 420 421 EAAGDGEGAGVLGLSASAECHLCPVCGESFASKGAQERHLRLLHAAQVFPCKYCPATFYS 480 481 SPGLTRHINKCHPSENRQVILLQVPVRPAC |
| Interface Residues: | 278, 279, 280, 281, 284, 285, 305, 306, 307, 308, 309, 310, 312, 313, 316, 327, 329, 330, 331, 332, 333, 334, 337, 340, 341, 342, 343, 344, 345, 348, 349, 350, 352, 353, 356, 362, 364, 365, 377, 378, 379, 380, 381, 384, 413, 415, 416, 419, 451, 452, 453, 454, 455, 457, 458, 461, 479, 480, 481, 482, 483, 485, 486, 490, 493 |
| 3D-footprint Homologues: | 5ei9_F, 4m9v_C, 6e94_A, 2i13_A, 7w1m_H, 1mey_C, 8ssq_A, 8ssu_A, 6u9q_A, 5kkq_D, 7txc_E, 5v3j_F, 3uk3_C, 5yj3_D, 8cuc_F, 7y3l_A, 6ml4_A, 7n5w_A, 1tf3_A, 2drp_D, 6wmi_A, 5und_A, 1llm_D, 5k5i_A, 5k5l_F, 2kmk_A, 1f2i_J, 5yel_A, 4x9j_A, 1g2f_F, 8gn3_A, 8h9h_G, 7ysf_A, 7eyi_G, 7y3m_I, 2lt7_A, 8gh6_A |
| Binding Motifs: | MA0155.1 TGymwGGGGkcr INSM1_HUMAN.H10MO.C|M01265 TKTmAGGGGGCr |
| Binding Sites: | MA0155.1.1 / MA0155.1.13 / MA0155.1.14 / MA0155.1.2 / MA0155.1.3 / MA0155.1.4 / MA0155.1.5 / MA0155.1.6 / MA0155.1.7 MA0155.1.10 / MA0155.1.11 / MA0155.1.12 / MA0155.1.8 / MA0155.1.9 MA0155.1.15 / MA0155.1.16 / MA0155.1.17 MA0155.1.18 / MA0155.1.19 MA0155.1.20 |
| Publications: | Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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