Transcription Factor

Accessions: T049220_1.02 (CISBP 1.02)
Names: T049220_1.02;, Zic5
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:C2H2 ZF
Length: 622
Pfam Domains: 439-462 Zinc-finger double domain
450-474 C2H2-type zinc finger
450-474 Zinc finger, C2H2 type
466-493 Zinc-finger double domain
480-504 C2H2-type zinc finger
510-534 C2H2-type zinc finger
510-534 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLVGPPAHSQRRAVAMHLHPRDLGTD 60
61 PGVASTALGPEHMAQASGQGPCPPSQGLPGLSQVPAPAARSVASGTHPGARTHPDGGGSS 120
121 GAQASAPPPPAPPLPPSQSSSPPPPPPPPPALSGYTATNSGGGSSSGKGHSRDFVLRRDL 180
181 SATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGMFISASGTYAGRDGGGSALFPALH 240
241 DSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGY 300
301 GAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPAPPPAPAPHPHHPHLPGAAGAFLRYMRQ 360
361 PIKRELICKWLDPEELAGPPASADSGVKPCSKTFGTMHELVNHVTVEHVGGPEQSSHVCF 420
421 WEDCPREGKPFKAKYKLINHIRVHTGEKPFPCPFPGCGKVFARSENLKIHKRTHTGEKPF 480
481 KCEFDGCDRKFANSSDRKKHSHVHTSDKPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPP 540
541 SPGALGYSSVGTPVGDPLSPVLDPTRSRSSTLSPQVTNLNEWYVCQASGAPSHLHTPSSN 600
601 GTTSESEDEEMYGNPEVMRTIH
Interface Residues: 396, 398, 399, 402, 426, 428, 432, 433, 434, 435, 436, 438, 439, 441, 442, 443, 445, 462, 463, 464, 465, 466, 468, 469, 470, 492, 493, 494, 495, 496, 497, 498, 499, 500, 502, 503, 523, 524, 525, 526, 527, 528, 529
3D-footprint Homologues: 5v3j_F, 1ubd_C, 7w1m_H, 7n5w_A, 1tf3_A, 1tf6_A, 6ml4_A, 4x9j_A, 8gn3_A, 5kkq_D, 5ei9_F, 2kmk_A, 2gli_A, 1g2f_F, 8h9h_G, 7eyi_G, 2i13_A, 6e94_A, 7ysf_A, 6wmi_A, 5k5i_A, 5und_A, 2lt7_A, 2jpa_A, 7y3l_A, 3uk3_C, 6jnm_A, 8cuc_F, 1llm_D, 6blw_A, 6u9q_A, 1mey_C, 7txc_E, 5kl3_A, 2drp_D, 1f2i_J, 8ssq_A, 4m9v_C, 7y3m_I, 6a57_A, 5k5l_F, 2wbs_A, 5yel_A, 5yj3_D
Binding Motifs: M0422_1.02 syrGGggGyc
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.