Transcription Factor

						

			
Accessions: 1gtw_B (3D-footprint 20231221), 1gu4_B (3D-footprint 20231221), 1gu5_B (3D-footprint 20231221), 1h8a_B (3D-footprint 20231221), 1hjb_B (3D-footprint 20231221)

			
Names: C/EBP beta, CAAT/ENHANCER BINDING PROTEIN BETA, CCAAT/enhancer-binding protein beta, CEBPB_HUMAN, LAP, LIP, Liver activator protein, Liver-enriched inhibitory protein, Nuclear factor NF-IL6, TCF-5, Transcription factor 5, CCAAT/ENHANCER BINDING PROTEIN BETA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17676
Length: 67
Pfam Domains:      3-56 Basic region leucine zipper
     4-62 bZIP transcription factor
Sequence: 
(in bold interface residues)		   1 DKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQKKVEQLSRELSTL   60
  61 RNLFKQL
Interface Residues: 11, 14, 15, 17, 18, 21, 22
3D-footprint Homologues: 1nwq_C, 6mg1_B, 2c9l_Z, 2dgc_A
Binding Motifs: 1gtw_AB gTGGCGyAAk
1gtw_B gTGGC
1gu4_AB TTrCGCAA
1gu4_B TTGc
1gu5_AB rTTGncCAA
1gu5_B cAAc
1h8a_ABC TCCGTTAnnnGTTGCGCCAC
1hjb_ABC TTTCCAAAnnnTGTGGTTG
Binding Sites: 1gtw_C
1gtw_D
1gu4_C
1gu4_D
1gu5_C
1gu5_D
1h8a_D
1h8a_E
			
Publications: Tahirov T.H, Sato K, Ichikawa-Iwata E, Sasaki M, Inoue-Bungo T, Shiina M, Kimura K, Takata S, Fujikawa A, Morii H, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Mechanism of c-Myb-C/EBP beta cooperation from separated sites on a promoter. Cell 108:57-70 (2002). [Pubmed]


Tahirov T.H, Inoue-Bungo T, Morii H, Fujikawa A, Sasaki M, Kimura K, Shiina M, Sato K, Kumasaka T, Yamamoto M, Ishii S, Ogata K. Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta. Cell 104:755-67 (2001). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.