Transcription Factor

						

			
Accessions: ZBTB7C_full (HumanTF 1.0)

			
Names: B4DKU0_HUMAN, cDNA FLJ60286, highly similar to Homo sapiens zinc finger and BTB domain containing 7C, ZBTB7C
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: B4DKU0
Notes: Ensembl ID: ENSG00000184828; Full protein sequence; TF family: znfC2H2; Clone source: Megaman
Length: 620
Pfam Domains:    24-127 BTB/POZ domain
  381-402 Zinc-finger double domain
  392-414 C2H2-type zinc finger
  392-414 Zinc finger, C2H2 type
  407-431 Zinc-finger double domain
  420-442 C2H2-type zinc finger
  434-459 Zinc-finger double domain
  448-469 C2H2-type zinc finger
  448-469 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MANDIDELIGIPFPNHSSEVLCSLNEQRHDGLLCDVLLVVQEQEYRTHRSVLAACSKYFK   60
  61 KLFTAGTLASQPYVYEIDFVQPEALAAILEFAYTSTLTITAGNVKHILNAARMLEIQCIV  120
 121 NVCLEIMEPGGDGGEEDDKEDDDDDEDDDDEEDEEEEEEEEEDDDDDTEDFADQENLPDP  180
 181 QDISCHQSPSKTDHLTEKAYSDTPRDFPDSFQAGSPGHLGVIRDFSIESLLRENLYPKAN  240
 241 IPDRRPSLSPFAPDFFPHLWPGDFGAFAQLPEQPMDSGPLDLVIKNRKIKEEEKEELPPP  300
 301 PPPPFPNDFFKDMFPDLPGGPLGPIKAENDYGAYLNFLSATHLGGLFPPWPLVEERKLKP  360
 361 KASQQCPICHKVIMGAGKLPRHMRTHTGEKPYMCTICEVRFTRQDKLKIHMRKHTGERPY  420
 421 LCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTRSDHLHRHIKRQSCRMARPRRG  480
 481 RKPAAWRAASLLFGPGGPAPDKAAFVMPPALGEVGGHLGGAAVCLPGPSPAKHFLAAPKG  540
 541 ALSLQELERQFEETQMKLFGRAQLEAERNAGGLLAFALAENVAAARPYFPLPDPWAAGLA  600
 601 GLPGLAGLNHVASMSEANN*
Interface Residues: 350, 352, 353, 356, 374, 375, 376, 377, 378, 380, 381, 383, 384, 387, 400, 401, 402, 403, 404, 405, 406, 409, 413, 430, 431, 432, 433, 434, 435, 436, 437, 438, 458, 459, 460, 461, 462, 463, 464, 465, 466, 469
3D-footprint Homologues: 6wmi_A, 6jnm_A, 8cuc_F, 7y3l_A, 7n5w_A, 5k5i_A, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 6ml4_A, 5v3j_F, 5kkq_D, 5ei9_F, 7eyi_G, 8h9h_G, 2lt7_A, 1tf6_A, 2i13_A, 7y3m_I, 6e94_A, 7ysf_A, 2jpa_A, 1ubd_C, 1hwt_C, 1tf3_A, 2kmk_A, 2gli_A, 5k5l_F, 4x9j_A, 1llm_D, 6blw_A, 6u9q_A, 5yel_A, 1mey_C, 7txc_E, 5kl3_A, 1g2f_F, 6a57_A, 3uk3_C, 8gn3_A, 2wbs_A, 1f2i_J, 2drp_D, 5yj3_D, 4m9v_C
Binding Motifs: ZBTB7C_full rcgACCACCgam
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.