Transcription Factor

						

			
Accessions: OLIG2_full (HumanTF 1.0)

			
Names: Fragment, OLIG2, OLIG2 protein, Q05BP9_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q05BP9
Notes: Ensembl ID: ENSG00000205927; Full protein sequence; TF family: bHLH; Clone source: hORFeome
Length: 324
Pfam Domains:   110-162 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMG   60
  61 SAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPELQQLRLKINSRERKR  120
 121 MHDLNIAMDGLREVMPYAHGPSVRKLSKIATLLLARNYILMLTNSLEEMKRLVSEIYGGH  180
 181 HAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAAVSS  240
 241 ASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGASGGFQHWGGMPCPCSMCQV  300
 301 PPPHHHVSAMGAGSLPRLTSDAK*
Interface Residues: 91, 92, 95, 96, 110, 113, 114, 116, 117, 118, 120, 121
3D-footprint Homologues: 1nwq_C, 2ypa_A, 6od3_F, 2ypa_B, 2ql2_D
Binding Motifs: OLIG2_full AmCATATGky
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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