Transcription Factor
Accessions: | 4hc9_A (3D-footprint 20231221) |
Names: | GATA-binding factor 3, GATA3_HUMAN, Trans-acting T-cell-specific transcription factor GATA-3 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P23771 |
Length: | 105 |
Pfam Domains: | 3-36 GATA zinc finger 57-89 GATA zinc finger |
Sequence: (in bold interface residues) | 1 RECVNCGATSTPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTSCANC 60 61 QTTTTTLWRRNANGDPVCNACGLYYKLHNINRPLTMKKEGIQTRN |
Interface Residues: | 12, 13, 15, 25, 29, 53, 63, 64, 65, 66, 67, 68, 69, 79, 83, 84, 87, 104 |
3D-footprint Homologues: | 3vd6_C, 4hc9_A, 4pu3_C, 3dfx_B, 1gat_A, 4gat_A |
Binding Motifs: | 4hc9_A TgAt |
Binding Sites: | 4hc9_Y 4hc9_Z |
Publications: | Chen Y, Bates D.L, Dey R, Chen P.H, Machado A.C, Laird-Offringa I.A, Rohs R, Chen L. DNA binding by GATA transcription factor suggests mechanisms of DNA looping and long-range gene regulation. Cell reports 2:1197-206 (2012). [Pubmed] |
Related annotations: | PaperBLAST |
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