Transcription Factor
| Accessions: | Q6NX45 (JASPAR 2024) |
| Names: | ZN774_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q6NX45 |
| Length: | 483 |
| Pfam Domains: | 153-173 C2H2-type zinc finger 153-173 C2H2-type zinc finger 153-173 Zinc finger, C2H2 type 166-190 Zinc-finger double domain 178-201 C2H2-type zinc finger 179-201 C2H2-type zinc finger 179-201 Zinc finger, C2H2 type 193-217 Zinc-finger double domain 207-229 Zinc finger, C2H2 type 207-229 C2H2-type zinc finger 207-229 C2H2-type zinc finger 222-245 Zinc-finger double domain 234-257 C2H2-type zinc finger 235-257 C2H2-type zinc finger 235-257 Zinc finger, C2H2 type 250-274 Zinc-finger double domain 263-285 C2H2-type zinc finger 263-285 Zinc finger, C2H2 type 263-285 C2H2-type zinc finger 280-301 Zinc-finger double domain 291-313 C2H2-type zinc finger 291-313 Zinc finger, C2H2 type 291-313 C2H2-type zinc finger 306-328 Zinc-finger double domain 319-341 C2H2-type zinc finger 319-341 Zinc finger, C2H2 type 319-342 C2H2-type zinc finger 334-357 Zinc-finger double domain 347-369 C2H2-type zinc finger 347-369 C2H2-type zinc finger 347-369 Zinc finger, C2H2 type 361-385 Zinc-finger double domain 375-395 C2H2-type zinc finger 375-397 C2H2-type zinc finger 375-397 Zinc finger, C2H2 type 390-413 Zinc-finger double domain 402-423 C2H2-type zinc finger 403-425 C2H2-type zinc finger 403-425 Zinc finger, C2H2 type 420-441 Zinc-finger double domain 431-453 Zinc finger, C2H2 type 431-453 C2H2-type zinc finger 431-453 C2H2-type zinc finger 446-469 Zinc-finger double domain 459-481 C2H2-type zinc finger 459-481 Zinc finger, C2H2 type 459-469 C2H2-type zinc finger |
| Sequence: (in bold interface residues) | 1 MWLGTSGKSGLPGHCLENPLQECHPAQLEEWALKGISRPSVISQPEQKEEPWVLPLQNFE 60 61 ARKIPRESHTDCEHQVAKLNQDNSETAEQCGTSSERTNKDLSHTLSWGGNWEQGLELEGQ 120 121 HGTLPGEGQLESFSQERDLNKLLDGYVGEKPMCAECGKSFNQSSYLIRHLRTHTGERPYT 180 181 CIECGKGFKQSSDLVTHRRTHTGEKPYQCKGCEKKFSDSSTLIKHQRTHTGERPYECPEC 240 241 GKTFGRKPHLIMHQRTHTGEKPYACLECHKSFSRSSNFITHQRTHTGVKPYRCNDCGESF 300 301 SQSSDLIKHQRTHTGERPFKCPECGKGFRDSSHFVAHMSTHSGERPFSCPDCHKSFSQSS 360 361 HLVTHQRTHTGERPFKCENCGKGFADSSALIKHQRIHTGERPYKCGECGKSFNQSSHFIT 420 421 HQRIHLGDRPYRCPECGKTFNQRSHFLTHQRTHTGEKPFHCSKCNKSFRQKAHLLCHQNT 480 481 HLI |
| Interface Residues: | 161, 162, 163, 164, 165, 189, 190, 192, 193, 195, 196, 217, 218, 219, 220, 221, 223, 224, 227, 245, 246, 247, 248, 249, 251, 252, 254, 255, 256, 258, 273, 274, 275, 276, 277, 278, 280, 301, 302, 303, 304, 305, 308, 309, 329, 330, 331, 332, 333, 334, 335, 336, 337, 357, 358, 359, 360, 361, 364, 385, 386, 387, 388, 389, 391, 392, 395, 413, 414, 415, 416, 417, 420, 426, 440, 442, 443, 444, 445, 447, 448, 452, 469, 470, 471, 473 |
| 3D-footprint Homologues: | 3uk3_C, 1tf3_A, 2kmk_A, 1tf6_A, 5yel_A, 8ssq_A, 6blw_A, 6u9q_A, 5kkq_D, 2lt7_A, 7n5w_A, 5ei9_F, 5kl3_A, 2drp_D, 7w1m_H, 2wbs_A, 8h9h_G, 7y3m_I, 6e94_A, 1ubd_C, 7txc_E, 5v3j_F, 2gli_A, 1f2i_J, 2jpa_A, 8ssu_A, 8cuc_F, 7y3l_A, 4m9v_C, 7ysf_A, 5k5i_A, 6ml4_A, 4x9j_A, 5yj3_D, 1g2f_F, 1llm_D, 5k5l_F, 6jnm_A, 8gn3_A, 6a57_A |
| Binding Motifs: | UN0656.1 msAGTGGACCACAAGCyrr UN0656.2 AGTGGACCACAAGCy |
| Binding Sites: | UN0656.1.1 UN0656.1.10 UN0656.1.11 UN0656.1.12 UN0656.1.13 UN0656.1.14 UN0656.1.15 UN0656.1.16 UN0656.1.17 UN0656.1.18 / UN0656.1.19 UN0656.1.19 / UN0656.1.20 UN0656.1.2 UN0656.1.20 UN0656.1.3 UN0656.1.4 UN0656.1.5 UN0656.1.6 UN0656.1.7 UN0656.1.8 UN0656.1.9 UN0656.1.18 UN0656.2.1 UN0656.2.10 UN0656.2.11 UN0656.2.12 UN0656.2.13 UN0656.2.14 UN0656.2.15 UN0656.2.16 UN0656.2.17 UN0656.2.18 UN0656.2.19 / UN0656.2.8 UN0656.2.2 UN0656.2.20 UN0656.2.3 UN0656.2.4 UN0656.2.5 UN0656.2.6 UN0656.2.7 UN0656.2.9 |
| Related annotations: | PaperBLAST |
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