Transcription Factor

Accessions: T085227_1.02 (CISBP 1.02), UP00319A (UniPROBE 20160601), Q07928 (JASPAR 2024)
Names: GAT3, T085227_1.02;, Protein GAT3, YLR013W, GAT3_YEAST
Organisms: Saccharomyces cerevisiae
Libraries: CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Description: Protein containing GATA family zinc finger motifs
Notes: experiment type:PBM, family:GATA
Length: 141
Pfam Domains: 72-104 GATA zinc finger
Sequence:
(in bold interface residues)
1 MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTAKPISASLYVTTNNTAVVQH 60
61 NVQKRKGVTRRCPQCAVIKTSPQWREGPDGEVTLCNACGLFYRKIFLVFGKDLAKRYFNE 120
121 IKGVSVKRKVPKSLYGVTRTR
Interface Residues: 81, 82, 83, 85, 96, 100, 101
3D-footprint Homologues: 3dfx_B, 3vd6_C, 1gat_A, 4hc9_A, 4gat_A
Binding Motifs: UP00319A_1 baaatbRGATCTACragctg
M0804_1.02 gtAGwTcyrw
MA0301.1 aGATCyamm
MA0301.2 aGATCy
Binding Sites: AAGATCTA
AGAACTAC
AGATCTAA
AGATCTAC
AGATCTAG
AGATCTAT
AGATCTCA
AGATCTCC
AGATCTGG
CAGATCTA
CGGATCTA
CGTAGATC
GAGATCTA
GAGATCTC
GATCTACA
GATCTACC
GGAACTAC
GGATCTAC
TAGATCCA
TAGATCTA
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]

Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.