Transcription Factor
| Accessions: | T085227_1.02 (CISBP 1.02), UP00319A (UniPROBE 20160601), Q07928 (JASPAR 2024) |
| Names: | GAT3, T085227_1.02;, Protein GAT3, YLR013W, GAT3_YEAST |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | CISBP 1.02 1, UniPROBE 20160601 2, JASPAR 2024 3 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Description: | Protein containing GATA family zinc finger motifs |
| Notes: | experiment type:PBM, family:GATA |
| Length: | 141 |
| Pfam Domains: | 72-104 GATA zinc finger |
| Sequence: (in bold interface residues) | 1 MNIKTLCHPEYKRISVESLLNPVEETIDCEKPHSQTKINTAKPISASLYVTTNNTAVVQH 60 61 NVQKRKGVTRRCPQCAVIKTSPQWREGPDGEVTLCNACGLFYRKIFLVFGKDLAKRYFNE 120 121 IKGVSVKRKVPKSLYGVTRTR |
| Interface Residues: | 81, 82, 83, 85, 96, 100, 101 |
| 3D-footprint Homologues: | 3dfx_B, 3vd6_C, 1gat_A, 4hc9_A, 4gat_A |
| Binding Motifs: | UP00319A_1 baaatbRGATCTACragctg M0804_1.02 gtAGwTcyrw MA0301.1 aGATCyamm MA0301.2 aGATCy |
| Binding Sites: | AAGATCTA AGAACTAC AGATCTAA AGATCTAC AGATCTAG AGATCTAT AGATCTCA AGATCTCC AGATCTGG CAGATCTA CGGATCTA CGTAGATC GAGATCTA GAGATCTC GATCTACA GATCTACC GGAACTAC GGATCTAC TAGATCCA TAGATCTA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] Badis G, Chan E.T, van Bakel H, Pena-Castillo L, Tillo D, Tsui K, Carlson C.D, Gossett A.J, Hasinoff M.J, Warren C.L, Gebbia M, Talukder S, Yang A, Mnaimneh S, Terterov D, Coburn D, Li Yeo A, Yeo Z.X, Clarke N.D, Lieb J.D, Ansari A.Z, Nislow C, Hughes T.R. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Molecular cell 32:878-87 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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