Transcription Factor
| Accessions: | 1h6f_A (3D-footprint 20231221) |
| Names: | T-box protein 3, T-BOX TRANSCRIPTION FACTOR TBX3, TBX3_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | O15119 |
| Length: | 184 |
| Pfam Domains: | 3-184 T-box |
| Sequence: (in bold interface residues) | 1 DPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDC 60 61 RYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTI 120 121 LNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAK 180 181 GFRD |
| Interface Residues: | 29, 161, 162, 178, 181, 182 |
| 3D-footprint Homologues: | 2x6v_A, 4a04_B, 1h6f_B, 5flv_I, 1xbr_B, 6f59_B |
| Binding Motifs: | 1h6f_AB TnnnCACctAGgTGnnnA |
| Publications: | Coll M, Seidman J.G, Müller C.W. Structure of the DNA-bound T-box domain of human TBX3, a transcription factor responsible for ulnar-mammary syndrome. Structure (London, England : 1993) 10:343-56 (2002). [Pubmed] |
| Related annotations: | PaperBLAST |
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