Transcription Factor

Accessions: 6chv_G (3D-footprint 20231221)
Names: Antidote protein, Antitoxin HigA, HIGA_PROVU, Host inhibition of growth protein A
Organisms: Proteus vulgaris
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q7A224
Length: 91
Pfam Domains: 12-61 Helix-turn-helix
Sequence:
(in bold interface residues)
1 VSHPGEMIARDLEDMGVSGRRFAHNIGVTPATVSRLLAGKTALTPSLSIRIAAALGSTPE 60
61 FWLRLQSNYDLRQLENQIDTSGIVLYGESNE
Interface Residues: 19, 20, 29, 30, 31, 32, 34, 35, 40, 41, 46
3D-footprint Homologues: 1per_L, 6chv_D, 6fix_D, 7csw_B
Binding Motifs: 6chv_GH TACAnnnnnTGTaanA
Publications: Schureck MA, Meisner J, Hoffer ED, Wang D, Onuoha N, Ei Cho S, Lollar P 3rd, Dunham CM. Structural basis of transcriptional regulation by the HigA antitoxin. Mol Microbiol 111:1449-1462 (2019). [Pubmed]
Related annotations: PaperBLAST

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