Transcription Factor

Accessions: 3uk3_D (3D-footprint 20231221), 4is1_D (3D-footprint 20231221)
Names: Zinc finger protein 217, ZN217_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O75362
Length: 54
Pfam Domains: 3-24 Zinc finger, C2H2 type
3-24 C2H2-type zinc finger
17-40 Zinc-finger double domain
30-53 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 SRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHK
Interface Residues: 10, 12, 13, 14, 15, 16, 18, 19, 20, 21, 22, 25, 27, 40, 41, 42, 43, 44, 45, 46, 47, 48, 51
3D-footprint Homologues: 8gn3_A, 7y3l_A, 7n5w_A, 3uk3_C, 7ysf_A, 2kmk_A, 1tf3_A, 6jnm_A, 8cuc_F, 5k5l_F, 2lt7_A, 8ssu_A, 1tf6_A, 6ml4_A, 5v3j_F, 4x9j_A, 1llm_D, 6blw_A, 5kkq_D, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 7txc_E, 6e94_A, 5kl3_A, 1f2i_J, 6wmi_A, 5k5i_A, 5und_A, 2gli_A, 1g2f_F, 8h9h_G, 4m9v_C, 7eyi_G, 2i13_A, 7y3m_I, 8ssq_A, 7w1m_H, 6a57_A, 2jpa_A, 1yuj_A, 2wbs_A, 5yel_A, 5yj3_D
Binding Motifs: 3uk3_CD TGCAGAATnnATTCTGCA
4is1_CD TGCAGAATnnATTCTGCA
4is1_D TGCAGAAT
Binding Sites: 3uk3_A / 3uk3_B / 4is1_A / 4is1_B
Publications: Vandevenne M, Jacques D.A, Artuz C, Nguyen C.D, Kwan A.H, Segal D.J, Matthews J.M, Crossley M, Guss J.M, Mackay J.P. New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. The Journal of biological chemistry 288:10616-27 (2013). [Pubmed]
Related annotations: PaperBLAST

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