Transcription Factor

Accessions: 1pdn_C (3D-footprint 20231221)
Names: PRD PAIRED, PRD_DROME
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P06601
Length: 123
Pfam Domains: 1-123 'Paired box' domain
21-60 Homeodomain-like domain
Sequence:
(in bold interface residues)
1 QGRVNQLGGVFINGRPLPNNIRLKIVEMAADGIRPCVISRQLRVSHGCVSKILNRYQETG 60
61 SIRPGVIGGSKPRIATPEIENRIEEYKRSSPGMFSWEIREKLIREGVCDRSTAPSVSAIS 120
121 RLV
Interface Residues: 13, 45, 46, 48, 50, 51, 67, 70, 73, 115, 116, 117, 118, 120, 121
3D-footprint Homologues: 1pdn_C, 6pax_A, 1k78_A
Binding Motifs: 1pdn_C CnTnACG
Binding Sites: 1pdn_A
1pdn_B
Publications: Xu W, Rould M.A, Jun S, Desplan C, Pabo C.O. Crystal structure of a paired domain-DNA complex at 2.5 A resolution reveals structural basis for Pax developmental mutations. Cell 80:639-50 (1995). [Pubmed]
Related annotations: PaperBLAST

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