Transcription Factor
| Accessions: | Q96EK4 (JASPAR 2024) |
| Names: | THA11_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q96EK4 |
| Length: | 314 |
| Pfam Domains: | 5-66 THAP domain |
| Sequence: (in bold interface residues) | 1 MPGFTCCVPGCYNNSHRDKALHFYTFPKDAELRRLWLKNVSRAGVSGCFSTFQPTTGHRL 60 61 CSVHFQGGRKTYTVRVPTIFPLRGVNERKVARRPAGAAAARRRQQQQQQQQQQQQQQQQQ 120 121 QQQQQQQQQQQQSSPSASTAQTAQLQPNLVSASAAVLLTLQATVDSSQAPGSVQPAPITP 180 181 TGEDVKPIDLTVQVEFAAAEGAAAAAAASELQAATAGLEAAECPMGPQLVVVGEEGFPDT 240 241 GSDHSYSLSSGTTEEELLRKLNEQRDILALMEVKMKEMKGSIRHLRLTEAKLREELREKD 300 301 RLLAMAVIRKKHGM |
| Interface Residues: | 25, 54, 55, 57, 58, 59 |
| 3D-footprint Homologues: | 2ko0_A |
| Binding Motifs: | MA1573.1 rrrACTACAwtTCCCAGma |
| Binding Sites: | MA1573.1.1 MA1573.1.10 MA1573.1.11 MA1573.1.12 MA1573.1.13 MA1573.1.14 MA1573.1.15 MA1573.1.16 MA1573.1.17 MA1573.1.18 MA1573.1.19 MA1573.1.2 MA1573.1.20 MA1573.1.3 MA1573.1.4 MA1573.1.5 MA1573.1.6 MA1573.1.7 MA1573.1.8 MA1573.1.9 |
| Publications: | Dejosez M, Levine SS, Frampton GM, Whyte WA, Stratton SA, Barton MC, Gunaratne PH, Young RA, Zwaka TP. Ronin/Hcf-1 binds to a hyperconserved enhancer element and regulates genes involved in the growth of embryonic stem cells. Genes Dev 24:1479-84 (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.