Transcription Factor

						

			
Accessions: 2hap_D (3D-footprint 20231221)

			
Names: CYP1 activatory protein, HAP1_YEASX, HEME ACTIVATOR PROTEIN, Heme activator protein 1, Heme-responsive zinc finger transcription factor HAP1
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0CS82
Length: 75
Pfam Domains:      9-42 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence: 
(in bold interface residues)		   1 KRNRIPLRCTICRKRKVKCDKLRPHCQQCTKTGVAHLCHYMEQTWAEEAEKELLKDNELK   60
  61 KLRERVKSLEKTLSK
Interface Residues: 15, 16, 17, 18, 20, 21
3D-footprint Homologues: 1hwt_C, 1pyi_A, 1zme_D, 7uik_T, 1d66_B, 3coq_A, 6gys_C, 7n5w_A
Binding Motifs: 2hap_CD CGCtntTATCGC
2hap_D ATAAnaGCG
Binding Sites: 2hap_A
2hap_B
			
Publications: King D.A, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nature structural biology 6:22-7 (1999). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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