Transcription Factor
| Accessions: | Q15562 (JASPAR 2024) |
| Names: | TEA domain family member 2, TEAD-2, TEAD2_HUMAN, Transcriptional enhancer factor TEF-4 |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q15562 |
| Length: | 447 |
| Pfam Domains: | 20-439 TEA/ATTS domain family |
| Sequence: (in bold interface residues) | 1 MGEPRAGAALDDGSGWTGSEEGSEEGTGGSEGAGGDGGPDAEGVWSPDIEQSFQEALAIY 60 61 PPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKSREIQSKLK 120 121 DQVSKDKAFQTMATMSSAQLISAPSLQAKLGPTGPQASELFQFWSGGSGPPWNVPDVKPF 180 181 SQTPFTLSLTPPSTDLPGYEPPQALSPLPPPTPSPPAWQARGLGTARLQLVEFSAFVEPP 240 241 DAVDSYQRHLFVHISQHCPSPGAPPLESVDVRQIYDKFPEKKGGLRELYDRGPPHAFFLV 300 301 KFWADLNWGPSGEEAGAGGSISSGGFYGVSSQYESLEHMTLTCSSKVCSFGKQVVEKVET 360 361 ERAQLEDGRFVYRLLRSPMCEYLVNFLHKLRQLPERYMMNSVLENFTILQVVTNRDTQEL 420 421 LLCTAYVFEVSTSERGAQHHIYRLVRD |
| Interface Residues: | 390, 394 |
| 3D-footprint Homologues: | 8s4t_A |
| Binding Motifs: | MA1121.1 hcACATTCCwgsc MA1121.2 ACATTCC |
| Binding Sites: | MA1121.1.1 MA1121.1.10 MA1121.1.11 MA1121.1.12 MA1121.1.13 MA1121.1.14 MA1121.1.15 MA1121.1.16 MA1121.1.17 MA1121.1.18 MA1121.1.19 MA1121.1.2 MA1121.1.20 MA1121.1.3 MA1121.1.4 MA1121.1.5 MA1121.1.6 MA1121.1.7 MA1121.1.8 MA1121.1.9 MA1121.2.18 MA1121.2.1 MA1121.2.10 / MA1121.2.11 / MA1121.2.12 / MA1121.2.14 / MA1121.2.15 / MA1121.2.17 / MA1121.2.20 / MA1121.2.4 / MA1121.2.5 MA1121.2.13 / MA1121.2.2 / MA1121.2.6 / MA1121.2.8 MA1121.2.16 MA1121.2.19 MA1121.2.3 MA1121.2.7 MA1121.2.9 |
| Publications: | Wasserman W.W, Fickett J.W. Identification of regulatory regions which confer muscle-specific gene expression. Journal of molecular biology 278:167-81 (1998). [Pubmed] |
| Related annotations: | PaperBLAST |
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