Transcription Factor

						

			
Accessions: Q12953 (JASPAR 2024)

			
Names: Q12953_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q12953
Length: 370
Pfam Domains:      6-88 short chain dehydrogenase
Sequence: 
(in bold interface residues)		   1 MARASEAVSRILEEWHKAKVEAMTLDLALLRSVQHFAEAFKAKNVPLHVLVCNAATFALP   60
  61 WSLTKDGLETTFQVNHLGHFYLVQLLPGMFCAAQLLPVSLWSPQSPIDLQILTTPWENWT  120
 121 SVASLQQKTTIGRCWLITGPSSATSSSPTSCTVASPTRGHVERSDRSWKYDVLQHSSQLV  180
 181 GVHTAVYLGEAFHQVHATGSCHHRVLCCCPRTGGSRRDVLQQLLPLHALTRSSERRDGPD  240
 241 PVGLSERLIQERLAASPAKWSSERMGTHTRPVCVPSRKCQAGPLPNVPPTQIRKSKGNKS  300
 301 IHNRVKNLKYQWEAGNSWGKVSLFWGWARHRSLCFLVVACLKVKTWLACRFRISLEKHQQ  360
 361 FSSFYCYRIA
Interface Residues: 296
3D-footprint Homologues: 3zi5_A
Binding Motifs: MA1950.1 rtaAACAGGAwryd
MA1950.2 taAACAGGAwr
			
Publications: Ibarra IL, Hollmann NM, Klaus B, Augsten S, Velten B, Hennig J, Zaugg JB. Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions. Nat Commun 11:124 (2020). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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