Transcription Factor
| Accessions: | Q8N393 (JASPAR 2024) |
| Names: | ZN786_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | Q8N393 |
| Length: | 782 |
| Pfam Domains: | 9-49 KRAB box 240-262 Zinc finger, C2H2 type 240-262 C2H2-type zinc finger 240-250 C2H2-type zinc finger 389-406 Zinc-finger double domain 412-435 Zinc-finger double domain 425-448 C2H2-type zinc finger 425-447 Zinc finger, C2H2 type 425-447 C2H2-type zinc finger 440-463 Zinc-finger double domain 453-470 C2H2-type zinc finger 453-475 Zinc finger, C2H2 type 453-475 C2H2-type zinc finger 468-490 Zinc-finger double domain 481-503 C2H2-type zinc finger 481-503 Zinc finger, C2H2 type 481-503 C2H2-type zinc finger 496-520 Zinc-finger double domain 509-531 Zinc finger, C2H2 type 509-531 C2H2-type zinc finger 509-532 C2H2-type zinc finger 524-546 Zinc-finger double domain 552-576 Zinc-finger double domain 565-587 Zinc finger, C2H2 type 565-587 C2H2-type zinc finger 565-588 C2H2-type zinc finger 580-602 Zinc-finger double domain 593-615 Zinc finger, C2H2 type 593-615 C2H2-type zinc finger 593-603 C2H2-type zinc finger 608-630 Zinc-finger double domain 621-643 Zinc finger, C2H2 type 621-643 C2H2-type zinc finger 652-670 C2H2-type zinc finger 664-685 Zinc-finger double domain 676-696 C2H2-type zinc finger 676-698 Zinc finger, C2H2 type 676-686 C2H2-type zinc finger 691-713 Zinc-finger double domain 704-714 C2H2-type zinc finger 704-726 C2H2-type zinc finger 704-726 Zinc finger, C2H2 type 719-741 Zinc-finger double domain 732-754 C2H2-type zinc finger 732-754 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAEPPRLPLTFEDVAIYFSEQEWQDLEAWQKELYKHVMRSNYETLVSLDDGLPKPELISW 60 61 IEHGGEPFRKWRESQKSGNIICSSVDMHFDPGFEEQLFWGSQQAMNSGKTKSHFQLDPES 120 121 QCSFGSFVSFRPDQGITLGSPQRHDARAPPPLACGPSESTLKEGIPGPRNLDLPGLWDVP 180 181 AWESTQHPWPVCGESCWENNHLVMHQRGHSKDRTRRAWEKFNKRAETQMPWSSPRVQRHF 240 241 RCGVCGKSFRRKLCLLRHLAAHTGRGPFRNADGEMCFRHELTHPSHRLPQQGEKPAQCTP 300 301 CGKRSLPVDSTQARRCQHSREGPASWREGRGASSSVHSGQKPGSRLPQEGNSHQEGDTEA 360 361 LQHGAEGPCSCSECGERSPMSARLASPCRAHTGEKPFQCAHCTKRFRLRRLLQVHQHAHG 420 421 GERPFSCRKCGKGFAKQCKLTEHIRVHSGEKPFRCAKCGRNFRQRGQLLRHQRLHTDEKP 480 481 FQCPECGLSFRLESMLRAHRLRHGGERPFSCSECGRGFTHQCKLREHLRVHSGERPFQCL 540 541 KCDKRFRLKGILKAHQHTHSKERPFSCGECGKGFTRQSKLTEHLRVHSGERPFQCPECNR 600 601 SFRLKGQLLSHQRLHTGERPFQCPECDKRYRVKADMKAHQLLHSGEMPFSCECGKGFVKH 660 661 SKLIEHIRTHTGEKPFQCPKCDKSFRLKAQLLSHQGLHTGERPFHCPECDKNFRERGHML 720 721 RHQRIHRPERPFACGDCGKGFIYKSKLAEHIRVHTKSCPAPNELDIKKRLSQLFAMIEAD 780 781 WS |
| Interface Residues: | 435, 436, 438, 439, 442, 463, 464, 465, 466, 467, 470, 474, 491, 492, 494, 495, 497, 498, 520, 521, 522, 523, 525, 526, 527, 528, 529, 530, 531, 537, 539, 547, 548, 549, 550, 551, 552, 553, 554, 556, 557, 558, 575, 576, 577, 578, 579, 581, 582, 583, 584, 585, 588, 593, 603, 604, 605, 606, 607, 608, 609, 610, 611, 631, 632, 633, 634, 635, 637, 638, 641, 659, 660, 661, 662, 665, 671, 685, 687, 689, 690, 693, 697, 714, 715, 716, 717, 718, 719, 742, 743, 745 |
| 3D-footprint Homologues: | 7y3l_A, 1llm_D, 6u9q_A, 5ei9_F, 8cuc_F, 3uk3_C, 7n5w_A, 7w1m_H, 5kkq_D, 8h9h_G, 5v3j_F, 8gn3_A, 5k5i_A, 8ssq_A, 5yj3_D, 1g2f_F, 7y3m_I, 2lt7_A, 6dnw_A, 2drp_D, 7txc_E, 6ml4_A, 2gli_A, 8ssu_A, 7ysf_A, 6e94_A, 1ubd_C, 6jnm_A, 1tf3_A, 6blw_A, 4x9j_A, 1f2i_J, 1tf6_A, 5kl3_A, 4m9v_C, 6a57_A, 2jpa_A, 2kmk_A, 5yel_A, 5k5l_F, 2wbs_A |
| Binding Motifs: | UN0659.1 sgCCCAGGCss UN0659.2 CCCAGGC |
| Binding Sites: | UN0659.1.11 UN0659.1.1 UN0659.1.10 / UN0659.1.20 UN0659.1.12 UN0659.1.13 UN0659.1.14 UN0659.1.15 UN0659.1.16 UN0659.1.17 UN0659.1.18 UN0659.1.19 UN0659.1.2 UN0659.1.20 UN0659.1.3 UN0659.1.4 / UN0659.1.7 UN0659.1.10 / UN0659.1.5 UN0659.1.11 / UN0659.1.6 UN0659.1.12 / UN0659.1.7 UN0659.1.15 / UN0659.1.8 UN0659.1.9 UN0659.2.15 UN0659.2.13 UN0659.2.10 / UN0659.2.11 / UN0659.2.16 / UN0659.2.17 / UN0659.2.18 / UN0659.2.5 / UN0659.2.8 UN0659.2.20 / UN0659.2.4 UN0659.2.2 UN0659.2.9 UN0659.2.6 / UN0659.2.7 UN0659.2.14 UN0659.1.13 UN0659.1.14 UN0659.1.16 UN0659.1.17 UN0659.1.18 UN0659.1.19 UN0659.1.3 UN0659.1.4 UN0659.1.5 UN0659.1.6 UN0659.1.8 UN0659.1.9 UN0659.2.1 UN0659.2.12 UN0659.2.19 UN0659.2.3 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.