Transcription Factor

						

			
Accessions: T134739_1.02 (CISBP 1.02)

			
Names: nhr-70, T134739_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 389
Pfam Domains:     10-78 Zinc finger, C4 type (two domains)
  163-372 Ligand-binding domain of nuclear hormone receptor
Sequence: 
(in bold interface residues)		   1 MSAGRGEKPPCSICGEVGNGVHFGAEACRACAAFFRRSVALNKLYRCRGDGNCDILSTIR   60
  61 CMCRACRFAKCMAVGMKREAVQKYRDAYGKRGSDVESPGSSSVSLPNQGDGFGPPGGFNP  120
 121 NSTFDSVEECGMPILTMLSQNYEKLQSVRRVVHHDQGSSVFQMRTPKAVSYKEANIVSSK  180
 181 ECDLVADWILNSYPGFADLHKDQKIILFRNFFLPFVILQGGHFACIHNRSDVIILASGDY  240
 241 IDCSHPETFYYDPDGRQLMSSEDAVRMFASSFSIYRRNVTDPMLRDNVDSFEFFALCSLV  300
 301 LFDTGLEGQSEECIRVSRRIREAIQREILYHYRNVRHIEDPSMRLANLLSLLPALQRATR  360
 361 RFQEDVEISHVFNVYSVDAKFYEMCNGRF
Interface Residues: 19, 20, 22, 23, 29, 30, 32, 33, 36, 37, 61, 85, 90, 91, 96, 247, 259
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 3g9m_B, 1a6y_A, 1lo1_A, 4oln_B, 7xvn_C, 5krb_G, 2han_B, 1kb2_B, 2a66_A, 8cef_H, 2nll_B, 1lat_A, 2ff0_A, 1dsz_A, 8hbm_B, 4umm_E, 3cbb_A, 7xv6_B, 4iqr_B, 2han_A, 1hcq_E, 5cbx_B, 3g6t_A, 1r4i_A, 7prw_B, 5cbz_E, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 8rm6_A, 6ceu_B
Binding Motifs: M1488_1.02 ttTGTAGyck
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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