Transcription Factor
Accessions: | Q96RI1 (JASPAR 2024) |
Names: | Bile acid receptor, Farnesoid X-activated receptor, Farnesol receptor HRR-1, NR1H4_HUMAN, Nuclear receptor subfamily 1 group H member 4, Retinoid X receptor-interacting protein 14, RXR-interacting protein 14 |
Organisms: | Homo sapiens |
Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
Uniprot: | Q96RI1 |
Length: | |
Binding Motifs: | MA1110.1 tcAATGACCyh MA1146.1 grGkTCAtTGACCyy MA1146.2 rGkTCAtTGACCy |
Binding Sites: | MA1110.1.1 MA1110.1.10 MA1110.1.11 MA1110.1.12 MA1110.1.13 MA1110.1.14 MA1110.1.15 MA1110.1.16 MA1110.1.17 MA1110.1.18 MA1110.1.19 MA1110.1.2 MA1110.1.20 MA1110.1.3 MA1110.1.4 MA1110.1.5 MA1110.1.6 MA1110.1.7 MA1110.1.8 MA1110.1.9 |
Publications: | Laffitte B. A., Kast H. R., Nguyen C. M., Zavacki A. M., Moore D. D., Edwards P. A. Identification of the DNA binding specificity and potential target genes for the farnesoid X-activated receptor.. J. Biol. Chem. 275:10638-10647 (2000). [Pubmed] Hoeke MO, Heegsma J, Hoekstra M, Moshage H, Faber KN. Human FXR regulates SHP expression through direct binding to an LRH-1 binding site, independent of an IR-1 and LRH-1. PLoS One : (2014). [Pubmed] |
Related annotations: | PaperBLAST |
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