Transcription Factor
| Accessions: | SOX5_MOUSE (HOCOMOCO 10), P35710 (JASPAR 2024) |
| Names: | SOX5_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P35710 |
| Length: | 763 |
| Pfam Domains: | 556-624 HMG (high mobility group) box 557-617 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 MLTDPDLPQEFERMSSKRPASPYGETDGEVAMVTSRQKVEEEESERLPAFHLPLHVSFPN 60 61 KPHSEEFQPVSLLTQETCGPRTPTVQHNTMEVDGNKVMSSLSPYNSSTSPQKAEEGGRQS 120 121 GESVSSAALGTPERRKGSLADVVDTLKQRKMEELIKNEPEDTPSIEKLLSKDWKDKLLAM 180 181 GSGNFGEIKGTPESLAEKERQLMGMINQLTSLREQLLAAHDEQKKLAASQIEKQRQQMEL 240 241 AKQQQEQIARQQQQLLQQQHKINLLQQQIQVQGQLPPLMIPVFPPDQRTLAAAAQQGFLL 300 301 PPGFSYKAGCSDPYPVQLIPTTMAAAAAATPGLGPLQLQQFYAAQLAAMQVSPGGKLLGL 360 361 PQGNLGAAVSPTSIHTDKSTNSPPPKSKDEVAQPLNLSAKPKTSDGKSPASPTSPHMPAL 420 421 RINSGAGPLKASVPAALASPSARVSTIGYLNDHDAVTKAIQEARQMKEQLRREQQALDGK 480 481 VAVVNSIGLSNCRTEKEKTTLESLTQQLAVKQNEEGKFSHGMMDFNMSGDSDGSAGVSES 540 541 RIYRESRGRGSNEPHIKRPMNAFMVWAKDERRKILQAFPDMHNSNISKILGSRWKAMTNL 600 601 EKQPYYEEQARLSKQHLEKYPDYKYKPRPKRTCLVDGKKLRIGEYKAIMRNRRQEMRQYF 660 661 NVGQQAQIPIATAGVVYPSAIAMAGMPSPHLPSEHSSVSSSPEPGMPVIQSTYGAKGEEP 720 721 HIKEEIQAEDINGEIYEEYDEEEEDPDVDYGSDSENHIAGQAN |
| Interface Residues: | 558, 561, 563, 564, 567, 571, 582, 583, 584, 587, 625 |
| 3D-footprint Homologues: | 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 1hry_A |
| Binding Motifs: | PB0176.1 wwtCatmAttwasdd SOX5_MOUSE.H10MO.C|M01349 yATTGTTw MA0087.1 ATTGTTw PB0072.1 wwdrgAACAATwaahw MA0087.2 rrsAACAATGGsm MA0087.3 AACAATGG |
| Binding Sites: | MA0087.3.11 / MA0087.3.12 / MA0087.3.4 / MA0087.3.7 MA0087.3.14 / MA0087.3.15 MA0087.3.13 / MA0087.3.9 MA0087.3.5 / MA0087.3.8 MA0087.3.18 MA0087.1.1 MA0087.1.10 MA0087.1.11 MA0087.1.12 MA0087.1.13 / MA0087.1.14 MA0087.1.15 MA0087.1.16 MA0087.1.17 MA0087.1.18 MA0087.1.19 MA0087.1.2 MA0087.1.20 MA0087.1.3 MA0087.1.4 MA0087.1.5 MA0087.1.6 MA0087.1.7 MA0087.1.8 MA0087.1.9 MA0087.2.1 MA0087.2.10 / MA0087.2.12 MA0087.2.11 / MA0087.2.13 MA0087.2.12 / MA0087.2.15 MA0087.2.13 / MA0087.2.18 MA0087.2.14 / MA0087.2.19 MA0087.2.15 / MA0087.2.20 MA0087.2.16 MA0087.2.17 MA0087.2.18 MA0087.2.19 MA0087.2.2 MA0087.2.20 MA0087.2.3 / MA0087.2.4 MA0087.2.4 / MA0087.2.5 MA0087.2.5 / MA0087.2.6 MA0087.2.6 / MA0087.2.7 MA0087.2.7 / MA0087.2.8 MA0087.2.10 / MA0087.2.8 MA0087.2.11 / MA0087.2.9 MA0087.2.14 MA0087.2.16 MA0087.2.17 MA0087.2.3 MA0087.2.9 MA0087.3.1 / MA0087.3.10 / MA0087.3.2 MA0087.3.16 MA0087.3.17 MA0087.3.19 MA0087.3.20 MA0087.3.3 MA0087.3.6 |
| Publications: | Denny P., Swift S., Connor F., Ashworth A. An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding protein. EMBO J. 11:3705-3712 (1992). [Pubmed] Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.