Transcription Factor
| Accessions: | T078276_1.02 (CISBP 1.02), FLI1_MOUSE (HOCOMOCO 10) |
| Names: | Fli1, T078276_1.02;, FLI1_MOUSE, Friend leukemia integration 1 transcription factor, Retroviral integration site protein Fli-1 |
| Organisms: | Mus musculus |
| Libraries: | CISBP 1.02 1, HOCOMOCO 10 2 1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] 2 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Notes: | experiment type:PBM, family:Ets |
| Length: | 452 |
| Pfam Domains: | 114-197 Sterile alpha motif (SAM)/Pointed domain 280-362 Ets-domain |
| Sequence: (in bold interface residues) | 1 MDGTIKEALSVVSDDQSLFDSAYGAAAHLPKADMTASGSPDYGQPHKINPLPPQQEWINQ 60 61 PVRVNVKREYDHMNGSRESPVDCSVSKCNKLVGGGEANPMNYNSYMDEKNGPPPPNMTTN 120 121 ERRVIVPADPTLWTQEHVRQWLEWAIKEYGLMEIDTSFFQNMDGKELCKMNKEDFLRATS 180 181 AYNTEVLLSHLSYLRESSLLAYNTTSHTDQSSRLNVKEDPSYDSVRRGAWNNNMNSGLNK 240 241 SPLLGGSQTMGKNTEQRPQPDPYQILGPTSSRLANPGSGQIQLWQFLLELLSDSANASCI 300 301 TWEGTNGEFKMTDPDEVARRWGERKSKPNMNYDKLSRALRYYYDKNIMTKVHGKRYAYKF 360 361 DFHGIAQALQPHPTETSMYKYPSDISYMPSYHAHQQKVNFVPSHPSSMPVTSSSFFGAAS 420 421 QYWTSPTAGIYPNPSVPRHPNTHVPSHLGSYY |
| Interface Residues: | 278, 333, 334, 336, 337, 338, 340, 341, 355 |
| 3D-footprint Homologues: | 3zp5_A, 7jsa_J, 8ee9_F, 4mhg_A, 2stt_A, 4uno_A, 3jtg_A, 1dux_F, 4lg0_B, 1yo5_C, 4bqa_A, 1awc_A, 4iri_A, 1bc8_C, 4l18_B |
| Binding Motifs: | M0699_1.02 rrcmGGAwry FLI1_MOUSE.H10MO.A|M01089 svrrCCGGAAGyggs |
| Related annotations: | PaperBLAST |
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